InSite Vision ( ISV) was leaping in late trading Thursday after the ophthalmic-products maker said pharmaceutical behemoth Pfizer ( PFE) granted it an exclusive license regarding Pfizer's patent family for treating eye infections with azithromycin.

As InSite's eye-infection treatment AzaSite contains azithromycin, the company says the license will "enhance the position and marketability of InSite's AzaSite franchise." Alameda, Calif.-based InSite was up 22 cents, or 13.1%, to $1.90. Pfizer shares were unchanged.

BSquare ( BSQR) surged after the Washington-based small-cap swung to a $706,000 profit, or 7 cents a share, in the fourth quarter, from last year's losses of $246,000, or 3 cents a share. The technical-software company also said sales climbed 11% to $14.1 million from a year ago. Shares were gaining 65 cents, or 18.6%, to $4.15.

Stockeryale ( STKR) jumped after the Salem, N.H.-based maker of lasers and LED modules narrowed its fourth-quarter operating losses to $1.7 million, or a nickel a share, from $4.7 million, or 17 cents a share, a year ago. Sales from continuing operations surged 45% to $5.9 million. The small-cap expects full-year 2007 sales will range between $30 million and $34 million, which would represent a significant increase from 2006's $19.4 million revenue. Shares were adding 23 cents, or 14.7%, to $1.80.

Postal stamp purveyor Stamps.com ( STMP) said it earned $5.1 million in the fourth quarter, excluding items, or 22 cents a share -- 2 cents above the Wall Street consensus, according to Thomson Financial. A year ago, the Los Angeles-based outfit had a profit of $4.1 million, or 17 cents a share. Sales were up 21% from last year to $25 million, $1 million above the mean target. Shares were rising $1.52, or 10.6%, to $15.82.

Buffalo Wild Wings ( BWLD) was soaring on impressive fourth-quarter results. The Minneapolis-based restaurant chain sailed past estimates, reporting income of $6.8 million, or 77 cents a share (including per-share gains of about 16 cents from an extra week this quarter) on sales that swelled 41.3% from a year ago to $83.3 million. Analysts were looking for 53 cents a share on $80.8 million revenue. Comparable sales rose 13.2% year over year at company-owned restaurants and 6.5% at franchises. Shares were bouncing $4.05, or 8.1%, to $54.03.

NightHawk Radiology ( NHWK) stock was lower after the Idaho-based company, which sells emergency radiology services, just missed fourth-quarter Street expectations. Adjusted income came to $4.6 million, or 15 cents a share, compared with $3.1 million, or 13 cents a share, a year ago. Analysts were projecting 16 cents a share. Revenue ballooned 30% to $24.1 million, which scrapes past the $24 million consensus. Shares were down $1.86, or 7.5%, to $22.90.

LTX ( LTXX) fell after it widened its losses on falling revenue. The Norwood, Mass., maker of semiconductor-testing equipment said it lost $3.1 million, or a nickel a share, compared with $1.4 million, or 2 cents a share, last year. This edges past Wall Street estimates by a penny, but revenue deflated to $34.7 million from $47.8 million a year ago -- a hair under the $34.9 million average projection. Shares were losing 35 cents, or 6.2%, to $5.30.