INSM) jumped 15.5% to $1.19 Wednesday after the company said the Italian Ministry of Health wants to make its drug Iplex available to patients with Lou Gehrig's disease there. Shares of Accentia Biopharmaceuticals ( ABPI) gained 6.3% to $4.20 after an audit of its majority-owned subsidiary Biovest International found that the company accurately disclosed information on the companies' consolidated businesses. Merrill Lynch upgraded Sanofi-Aventis ( SNY) to buy from neutral, citing improved prospects of a legal victory and the expected launch of its obesity drug in the U.S. Shares were up 28 cents to $44.81. Among other health stock winners Wednesday were Myriad Genetics ( MYGN), up 1.9% to $33.07; Quigley ( QGLY), gaining 7.9% to $6.43; Sunesis Pharmaceuticals ( SNSS), rising 5% to $5.24; Dyax ( DYAX), up 4.1% to $3.0; and Vertex Pharmaceuticals ( VRTX), rising 3.9% to $35.20. Among the losers were Polydex Pharmaceuticals ( POLXF), whose shares sank 9.7% to $6.45; Dr. Reddy's Laboratories ( RDY), falling 3.1% to $17.31; Gentium ( GENT), off 1.9% to $17.64; Incyte ( INCY), down 3.8% to $6.79; Gilead Sciences ( GILD), off 1.2% to $64.22; and Schering-Plough ( SGP), falling 1.2% to $23.70.