Today's Small-Cap Winners and Losers

Genta's (GNTA) shares were rising on news the Food and Drug Administration has accepted the biotech company's new drug application for the Genasense injection.

The company wants to use Genasense, which has had a rocky history, along with fludarabine and cyclophosphamide for treating patients with relapsed or refractory chronic lymphocytic leukemia. Shares of Genta gained 8 cents, or 2.9%, to $2.87.

Genaera ( GENR) saw its shares fall 5% after the company posted a fourth-quarter loss of $7.8 million, or 11 cents a share, on revenue of $42,000. The biopharmaceutical company lost $4.9 million, or 8 cents a share, with revenue of $29,000 in the year-ago period. Shares were losing 9 cents to $1.65.

Harris & Harris ( TINY) was climbing after Punk Ziegel raised its price target on the venture capital company's stock to $19 from $16.50. Shares of Harris & Harris were up 87 cents, or 6.6%, to $14.09.

MSGI Security Solutions ( MSGI) advanced 3.3% after the company said it received contracts for security products and services with two foreign governments. The exact nature of the contracts in Europe and the broader Middle East are confidential.

However, MSGI said the contracts establish long-term relationships that will result in at least $2 million in revenue over the next two years. Separately, MSGI has formally started operations in the Caribbean. Shares of MSGI were up 12 cents to $3.77.

Shares of Carrington Laboratories ( CARN) were skyrocketing after the company said its DelSite Biotechnologies unit selected Invitrogen's ( IVGN) PD-Direct services to develop a process for a cell-based avian H5 influenza antigen that will be used in a nasal vaccine.

DelSite is developing a nasal powder vaccine for pandemic avian influenza that combines its GelVac vaccine delivery system with an avian H5 influenza whole virion antigen. Carrington, a biopharmaceutical company, was jumping $1.79, or 39.5%, to $6.34.

FX Energy ( FXEN) shares were plunging following word from the company that the Drozdowice-1 well in western Poland will be plugged and abandoned. A drillstem test of the target reservoir yielded no observable hydrocarbons, FX said. The stock was dropping $1.03, or 18.6%, to $4.50.

Shares of Dril-Quip ( DRQ) rose after the drilling-equipment maker beat Wall Street's fourth-quarter earnings expectations. The company earned $11.7 million, or 63 cents a share, compared with $3.9 million, or 22 cents a share, a year ago. Revenue rose 66% to $94.9 million.

Analysts were looking for earnings of 55 cents a share. For the first quarter, Dril-Quip is projecting a profit of 55 cents to 65 cents a share, excluding any charges. The consensus estimate is 55 cents. Dril-Quip climbed $5.86, or 11.5%, to $56.66.

Five Star Quality Care ( FVE) moved higher after the operator of senior-living communities said its fourth-quarter earnings from continuing operations, excluding a charge, were $3.6 million, or 18 cents a share. Analysts were expecting earnings of 11 cents. Fourth-quarter revenue increased 20% to $199.8 million. Five Star Quality Care gained 61 cents, or 7.4%, to $8.91.

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