On a big day for bank earnings, Wells Fargo ( WFC) stood out, posting a 13% gain in third-quarter profits. The San Francisco-based lender, the nation's fifth largest bank, earned $1.98 billion, or $1.16 a share, up from $1.75 billion, or $1.02 a share, a year ago. Revenue at Wells Fargo increased 16% to $8.5 billion. Wells Fargo's earnings came in a penny ahead of the Thomson Financial consensus estimate. Revenue at the bank easily surpassed the consensus estimate of $8.1 billion. The bank's big home mortgage business was a strong performer in the quarter. Revenue from the division rose $487 million to $1.4 billion in the quarter. Of course, Wells Fargo may have difficulty duplicating that feat the rest of the year now that the average interest rate on a 30-year fixed mortgage has moved above 6%. With mortgage rates moving to new highs in recent weeks, most analysts expect the market for home refinancings and home equity lines to dry up. Wells Fargo also posted strong growth in consumer and commercial loans compared with a year ago. The dollar volume of consumer loans, which doesn't include mortgages, was up 4%. Loans to businesses were up 14%, a sign of economic vigor. "We continued to see solid commercial loan growth in asset-based lending, middle market, specialized financial services, commercial real estate and small business banking, including business direct," the bank said in a press release. But elsewhere in the banking world, the earnings news wasn't as good. Cincinnati-based Fifth Third ( FITB) said its earnings fell 13%, as the bank's net interest income declined in the face of the tight spread between long- and short-term interest rates. In the quarter, Fifth Third earned $395 million, or 71 cents a share, compared to $471 million, or 83 cents, a year ago. Revenue fell 1% to $1.37 billion.