Updated from 2:38 p.m. EDT

Shares of Biosite ( BSTE) were among the best-performing health care stocks Friday after the company said second-quarter earnings and sales would be better than anticipated.

The San Diego, Calif.-based company now expects to earn 57 cents to 62 cents a share on sales of $60 million. Previously, it said it would earn 46 cents to 55 cents a share on sales of $53 million to $58 million. Analysts polled by Thomson First Call had expected it to earn 49 cents a share on sales of $55 million. The company attributed the upbeat outlook to better gross margins and success in sustaining its Triage BNP market share. Shares of Biosite traded up $3.18, or 7.4%, to $46.

ICU Medical ( ICUI) fell after it reported weaker-than-expected second-quarter earnings and sales. It earned 23 cents a share on sales of $21.7 million. Analysts had expected it to earn 29 cents a share on sales of $25 million. A year ago ICU earned 26 cents a share on sales of $21.3 million. Shares of ICU Medical traded down $3.05, or 10.2%, to $26.95.

Shares of Bradley Pharmaceuticals ( BDY) rose after Standard & Poor's said it would add the company to its S&P Small Cap 600 Index. Bradley will replace Seacoast Financial Services ( SCFS), which is being acquired by Sovereign Bancorp ( SOV). The change is expected to take place after the close of trading on July 23. Shares of Bradley Pharmaceuticals traded up 94 cents, or 3.7%, to $26.10.

Xenogen ( XGEN) rose on its first day as a publicly traded company. The biotech concern priced 4.2 million shares at $7 apiece, raising a little more than $29 million. It had expected to sell shares for $8, which had been reduced from an earlier range of $9 to $11. Thomas Weisel Partners led the underwriting syndicate, which included CIBC World Markets and JMP Securities. Shares of Xenogen traded up 50 cents, or 7.1%, to $7.50.

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