What works? Jim Cramer says to invest in companies that make things, at a profit, and return some of those profits to shareholders while maintaining a reasonable share price for its growth rate.

A brief snapshot of some medical breakthroughs that are among the costliest in the world.

Stock futures slip lower as Covid worries and inflation concerns come into focus; AstraZeneca gets FDA nod for its antibody treatment; Jefferies sends bankers home after NY Covid outbreak; Amazon hit with record $1.3 billion fine in Italy and GameStop unveils a wider third quarter loss and details of a new SEC subpoena.

GlaxoSmithKline says its antibody drug was 'deliberately designed with a mutating virus in mind.'

Pharmaceutical titan AstraZeneca announces the FDA has granted priority review for its drug Lynparza used to treat breast cancer after chemotherapy.

Sequoia Capital and Y Combinator have told startups that cutting costs is a priority.

Elon Musk will soon allow Dogecoin to purchase SpaceX merchandise.

The theme park company has opened Guardians of the Galaxy: Cosmic Rewind and not everyone is happy despite the ride getting wonderful reviews.

Aurora is slashing its production capacity as it builds a runway toward positive Ebitda a year from now.