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Acusphere, Inc. (ACUS.
NPS Pharma regains ground.
BioCryst continues to fall on study results.
Small-caps lagged the major indices, weighed by drugmakers such as Acusphere.
24/7 Real Media climbs on reports of a buyout bid.
Ilumina jumps after the company says first-quarter results will top its guidance.
Fourth quarter set to be most active in a year but flood of biotech issues brings weak results.
The poor performance by a pair of offerings suggests the string of IPOs lined up might have to sit awhile.
Shares of the biotech IPO are up 13% in early trading.
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