NEW YORK (TheStreet) -- After initially being halted on Monday morning, shares of Isis Pharmaceuticals (ISIS) are rallying 4.5% after signing a $155 million deal with Bayer

The company's thrombosis drug is very important, as it acts as a blood thinner without causing the patient to bleed out, TheStreet's Jim Cramer, portfolio manager of the Action Alerts PLUS portfolio, said on CNBC's "Stop Trading" segment. 

This is a very big drug and a very big milestone, but investors should wait to hear what Dr. Stanley Crooke has to say when the company's CEO meets with Cramer on tonight's "Mad Money" TV show. 

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Turning to Tesla Motors (TSLA) - Get Report, Cramer says the stock has become a "battleground" between bulls and bears. Investors seem to expect weak earnings results from the automaker when it reports on Wednesday after the close. 

With these types of companies that have a lot of potential but also a very high valuation, investors either buy into the story or they don't. Right now, there don't seem to be a lot of people buying in, Cramer said.