DELAFIELD, Wis. (Stockpickr) -- Professional traders running mutual funds and hedge funds don't just look at a stock's price moves; they also track big changes in volume activity. Often when above-average volume moves into an equity, it precedes a large spike in volatility.

Major moves in volume can signal unusual activity, such as insider buying or selling -- or buying or selling by "superinvestors."

Unusual volume can also be a major signal that hedge funds and momentum traders are piling into a stock ahead of a catalyst. These types of traders like to get in well before a large spike, so it's always a smart move to monitor unusual volume. That said, remember to combine trend and price action with unusual volume. Put them all together to help you decipher the next big trend for any stock.

With that in mind, let's take a look at several stocks rising on unusual volume recently.

SolarWinds

SolarWinds(SWI) - Get Report, together with its subsidiaries, designs, develops, markets, sells and supports enterprise-class information technology and infrastructure management software to IT and DevOps professionals in various organizations worldwide. This stock is trading up 1.7% to $37.92 in Monday's trading session.

  • Monday's Volume: 799,000
  • Three-Month Average Volume: 842,924
  • Volume % Change: 283%

From a technical perspective, SolarWinds is spiking higher here right above some near-term support at $36 with strong upside volume flows. This stock recently gapped down sharply from over $46 to $35 with heavy downside volume flows. Following that move, shares of SolarWinds have now started to rebound sharply and it's quickly moving within range of triggering a big breakout trade. That trade will trigger if this stock manages to take out some near-term overhead resistance levels at $38 to its gap-down-day high of just over $40 with high volume.

Traders should now look for long-biased trades in SolarWinds as long as it's trending above some key near-term support at $36 and then once it sustains a move or close above those breakout levels with volume that hits near or above 842,924 shares. If that breakout begins soon, then this stock will set up to re-fill some of its previous gap-down-day zone that started above $46 a share.

United Rentals

United Rentals(URI) - Get Report, through its subsidiaries, operates as an equipment rental company. This stock is trading up 2.3% to $66.22 in Monday's trading session.

  • Monday's Volume: 1.76 million
  • Three-Month Average Volume: 2.54 million
  • Volume % Change: 92%

From a technical perspective, United Rentals is spiking notably higher here right above some near-term support at $62.46 with decent upside volume flows. This stock has been downtrending over the last two months and change, with shares moving lower from its high of $105.83 to its recent low of $62.46. During that move, shares of United Rental have been making mostly lower highs and lower lows, which is bearish technical price action. That said, this stock has now started to spike off that $62.46 low and it's beginning to move within range of triggering a near-term breakout trade. That trade will hit if this stock manages to take out some key near-term overhead resistance at around $67.50 with high volume.

Traders should now look for long-biased trades in United Rentals as long as it's trending above that recent low of $62.46 and then once it sustains a move or close above $67.50 with volume that hits near or above 2.54 million shares. If that breakout hits soon, then this stock will set up to re-test or possibly take out its next major overhead resistance levels at $70 to $75.

Amgen

Amgen(AMGN) - Get Report, a biotechnology company, discovers, develops, manufactures and delivers human therapeutics worldwide. This stock is trading up 2.7% to $162.98 in Monday's trading session.

  • Monday's Volume: 2.42 million
  • Three-Month Average Volume: 3.11 million
  • Volume % Change: 89%

From a technical perspective, Amgen is ripping sharply higher here and counter-trending versus the overall market weakness right off its 50-day moving average of $158.62 with decent upside volume flows. This move to the upside on Monday is now quickly pushing shares of Amgen within range of triggering a big breakout trade. That trade will hit if this stock manages to take out some key near-term overhead resistance levels at $165.59 to around $166 with high volume.

Traders should now look for long-biased trades in Amgen as long as it's trending above its 50-day at $158.62 or above its 200-day at $157.51 and then once it sustains a move or close above those breakout levels with volume that hits near or above 3.11 million shares. If that breakout gets underway soon, then this stock will set up to re-test or possibly take out its next major overhead resistance levels at $168 to $172.75, or its 52-week high of $173.60.

Inotek Pharmaceuticals

Inotek Pharmaceuticals  (ITEK) , a clinical-stage biopharmaceutical company, focuses on the discovery, development and commercialization of therapies for glaucoma. This stock is trading up 3.9% to $18.62 in Monday's trading session.

  • Monday's Volume: 3.26 million
  • Three-Month Average Volume: 1.11 million
  • Volume % Change: 415%

From a technical perspective Inotek Pharmaceuticals is ripping higher here right above some near-term support at around $15 with strong upside volume flows. This stock has made an incredible run over the last few trading sessions, with shares exploding higher from under $8 to its recent high of $19.45 a share. That move has now pushed shares of Inotek Pharmaceuticals into overbought territory, since its current relative strength index reading is 95. Overbought can always get more overbought, so shares of Inotek Pharmaceuticals could be setting up for more upside if it breaks out soon. That trade will hit if this stock manages to take out its all-time high of $19.45 with high volume.

Traders should now look for long-biased trades in Inotek Pharmaceuticals as long as it's trending above Monday's intraday low of $15.81 and then once it sustains a move or close above its all-time high of $19.45 with volume that registers near or above 1.11 million shares. If that breakout develops soon, then this stock will set up to enter new all-time-high territory, which is bullish technical price action. Some possible upside targets off that move are $22 to $23, or even $25 a share.

This article is commentary by an independent contributor. At the time of publication, the author held TK positions in the stocks mentioned.