Investors were taking some profits after the close Wednesday, but most of the big tech issues with

massive run-ups in regular trading were staying close to their 4 p.m. EDT closing levels.

Cisco

(CSCO) - Get Report

, whose earnings report after the close Tuesday fueled huge gains for the

Dow Jones Industrial Average and the

Nasdaq, was slipping 0.9% to $16.12. In regular trading, Cisco rose 24% to $16.27.

Other widely held tech names were giving back a few pennies.

Sun Micro

(SUNW) - Get Report

was down 0.3% to $6.87.

Dell

(DELL) - Get Report

was losing 0.2%, and

Microsoft

(MSFT) - Get Report

was lower by 0.4%.

Applied Materials

(AMAT) - Get Report

was off 0.7%, and

Oracle

(ORCL) - Get Report

was inching down 0.5%.

Intel

(INTC) - Get Report

and

Qualcomm

(QCOM) - Get Report

were flat. The

Nasdaq 100 Unit Trust

(QQQ) - Get Report

was tacking on 0.1% to $31.79, and

Sprint PCS

(PCS)

was better by 0.4% to $11.45.

McDonald's

(MCD) - Get Report

was the most active stock on Instinet, and the shares were adding 0.2% to $28.95. Overall, volume was moderate. In the first 90 minutes of trading, around 3.3 million shares changed hands among the top-20 volume leaders.

Pixar

(PIXR)

, the digital animation studio, was rising 7% to $44.01 after the company easily topped analysts' estimates for the latest quarter. The big winner was

NaPro BioTherapeutics

(NPRO)

after the company and partner

Abbott Laboratories

(ABT) - Get Report

received approval from the

Food and Drug Administration

to market an anticancer product. NaPro was higher by 73% to $9.50 after the news came out.