The Nasdaq closed up 0.68% to 11,775.
The Dow Jones Industrial Average ended down 223 points, or 0.78%, to 28,430 and the S&P 500 slipped 0.22% to 3,500.
The Dow posted its best August since 1984 and the S&P since 1986.
On Friday, the S&P 500 closed at a record for the sixth straight session and the Nasdaq also set a record. The Dow moved into positive territory for the year.
Stocks got a boost last week from Federal Reserve Chairman Jerome Powell’s comments that the central bank would keep interest rates low even if inflation rises above its target levels.
Salesforce.com (CRM) - Get Report, Amgen (AMGN) - Get Report and Honeywell (HON) - Get Report have joined the blue-chip Dow index, replacing Exxon Mobil (XOM) - Get Report, Pfizer (PFE) - Get Report and Raytheon Technologies (RTX) - Get Report, respectively.
Apple rose 3.4% to $129.04 while Tesla soared 13% to $498.32.
Shares of Microsoft (MSFT) - Get Report, Walmart (WMT) - Get Report and Oracle (ORCL) - Get Report - bidders for the U.S. operations of TikTok, the short-video app - traded lower after China updated its list of technologies subject to export restrictions, complicating a sale of the ByteDance unit.
Coronavirus infections in the United States have risen to 6,002,615, according to Johns Hopkins University, while confirmed deaths have passed 183,200. The U.S. leads the world in both categories.
In India, 78,761 new coronavirus cases were recorded Sunday, the highest one-day total for any country in the world since the pandemic was declared in early March.