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NEW YORK (TheStreet) -- Shares of NeoStem  (NBS) plummeted 25.52% to $5.05 in late morning trading Tuesday after the biotech company announced poor results from a trial of its proprietary cardiac stem-cell therapy NBS10.

NBS10, which used to be called AMR-001, missed two primary endpoints in the study to test the therapy's efficacy. The stem-cell therapy comes from a patient's own bone marrow and is injected into patients after a heart attack. The stem cells are then supposed to help blood flow and build cardiac muscle.

NeoStem's trial used non-invasive imaging to monitor blood flow through the heart six months after a one dose of NBS10 or a placebo. The study showed no difference between NBS and placebo, NeoStem said.

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The company announced the data at the American Heart Association annual meeting on Monday.

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