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The Apple (AAPL) - Get Report  effect was in full force Wednesday, after the world's largest company disappointed Wall Street Tuesday night. The news weighed on the U.S. equities market, as company after company reported positive earnings but traded lower on weak guidance or skepticism over growth prospects.

Though Action Alerts Plus holding Apple, and earnings from fellow AAP name Comcast (CMCSA) - Get Report  , as well as Coca-Cola (KO) - Get Report and Southwest (LUV) - Get Report  dominated the trading day, tech giant Microsoft (MSFT) - Get Report  unveiled a host of new features to its Surface tablet -- yes, the same tablet New England Patriot's head coach denounced this weekend.

The Dow Jones Industrial Average finished 0.17% higher, thanks to an earnings-driven rally in Boeing (BA) - Get Report  shares, while the Nasdaq closed down 0.63%. The S&P 500 ended 0.17% lower. Elsewhere, crude prices settled at a three-week low, with West Texas Intermediate (WTI) crude 1.66% lower at $49.13 a barrel.

But while the world of Wall Street (and TheStreet, too, of course) was focused on earnings, TheStreet and its affiliates were also hard at work hammering out exclusive news today on everything from a continued wave of M&A transactions to MasterCard's (MA) - Get Report latest plans to revolutionize the electronic payments industry to the rise of the pet insurance industry to who's coming to challenge Mylan (MYL) - Get Report in the EpiPen market. 

Here are the highlights from TheStreet and its affiliates:

Pardon Me, but I Have a Few Things to Say... Vertex, Biogen, Ariad, Sarepta
More about Vertex' Debbie Downer gene, Biogen's (BIIB) - Get Report Alzheimer's spin and Sarepta (SRPT) - Get Report caught in drug launch purgatory. Full story

Pet Insurer Trupanion Is No Dog
The company originally offered shares at $10 each in July 2014, but the stock has shot up 43.1% since then to $16.31 and sources don't see the run stopping anytime soon. Full story

Video of the Day: Here's How 'Pepper' the Robot is Helping MasterCard Process Payments

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TheStreet visited MasterCard's New York Technology Hub, where Jeannie Hii, MasterCard labs marketing business leader, showed us how some of their new payment innovations work. Full story

Carrizo Likely Next to Offer up Assets Following Spate of Energy Deals
The Houston company might now look to shop its Delaware Basin assets in West Texas, according to company followers, after picking up Sanchez' noncore Eagle Ford properties in South Texas. Full story

Tweet of the Day:

Here's How Your Refrigerator Broke the Internet
Recent hacks didn't just bring down some of the biggest websites online; it also revealed a frightening weakness in the Internet of Things. Full story

This story is part of a special series "The Internet of Things: Beyond the Hype." To Learn more about the IoT and the companies it affects, click here.

Chart of the Day: Ford Under the Hood

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If you thought that everything out of Detroit looks the same and that all domestic automakers are the same you haven't looked at the charts of Ford Motor (F) - Get Report . Full story

What Apple's iPhone 7 Sales Mean for Suppliers
Some positive news about Apple's iPhone sales wasn't enough to boost shares of Broadcom, Cirrus Logic and other major suppliers on Wednesday. Now what? Full story