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LONDON -- A modest rise in pharmaceutical stocks and a few select retailers couldn't hide what was, overall, a fairly depressing day in the UK. The FTSE 100 tried to shrug off events stateside for most of the day, but once Wall Street started moving lower again, it seemed to have no choice but to play follow the U.S. leader.

By the close, the FTSE 100 stood 66 points lower, or 1.0%, at 6302. The tech sector looked even more out of sorts, with the

Techmark 100

down 102 points, or 3.0%, to 3356.

Unsurprisingly after


woes, optical-component maker

Bookham Technology


was the blue-chip index's biggest loser, shedding 11.3% to

21.50 ($31.18).

Baltimore Technologies


was also under pressure, despite signing a major deal with



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for the development of mobile Internet security. The stock initially rose nearly 4% to an intraday high of 572p, but fell back to close 4.4% lower at 527.

Among the chip designers,

ARM Holdings


lost 3.4% to 652p, while

Parthus Technologies

(PRTH) - Get Priority Technology Holdings, Inc. Report

felt the pressure from an imminent share placing and tumbled 7.5% to 248p.

Drug stocks provided some level of support.


moved up 1.5% to

32.16 despite being downgraded by many brokers following poor earnings results Wednesday. Elsewhere in the sector,

Shire Pharmaceuticals

rose 2.6% to


In the media sector,

Granada Media


Carlton Communications

sold off on fears about advertising revenues. Granada fell 7.1% to 368, while Carlton lost 6.3% to 534.



bucked the trend by rising 2.7% to 885 ahead of next week's earnings.

Europe's other stock markets finished on a mixed note, as the

CAC 40

in Paris ended down 69.5, or 1.1%, at 6208.4 but the

Xetra Dax

in Frankfurt was up 47.7, or 0.7%, at 6795.9 late in German trading. The Neuer Markt's tech-heavy

Nemax 50

index was up 14.1, or 0.3%, at 4623.1.

French telecom-equipment maker



continued to suffer from worries surrounding rival



. After tanking 8% on Wednesday, Alcatel dropped a further 3.90 euros, or 5.3%, to 70.50 ($58.37).

Elsewhere in Paris,

France Telecom


ended down 4.00 euros, or 3.3%, to 119.00 and


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fell 0.49 euros, or 1.3%, to 37.43.

In Frankfurt,



fell 0.63 euros, or 1.2%, to 51.95, after releasing disappointing third-quarter earnings. Rival



fell 0.70 euros, or 1.3%, to 53.40.


Deutsche Telekom

(DT) - Get Dynatrace, Inc. Report

helped prop up the Dax, rising 1.23 euros, or 3%, to 42.58.