Here are five things you must know for Wednesday, April 25:  

1. -- Stocks Slumps Across the Globe

U.S. stock futures pointed to further losses for Wall Street and global stocks slumped on Wednesday, April 25, as investors retreated from expensive equity markets amid rising bond yields, concerns over the potential of earnings in the tech sector, and simmering geopolitical risks in commodity markets.

Contracts tied to the Dow Jones Industrial Average fell 100 points, while those linked to the broader S&P 500 were down 12.75 points. Futures for the Nasdaq declined 33.75 points.

Stocks finished sharply lower on Tuesday, April 24, as corporate earnings disappointed and the yield on the 10-year Treasury traded above 3% for the first time in four years. The Dow  tumbled 424 points, or 1.74%, to 24,024, for its biggest decline in three weeks. The S&P 500 fell 1.34% and the Nasdaq  slid 1.7%.

A selloff in the tech sector on Tuesday was led by a plunge of 4.8% in shares of Alphabet Inc. (GOOGL) , which tumbled after the Google parent posted a 73% jump in profit but also a rise in expenses

The U.S. economic calendar on Wednesday includes Oil Inventories for the week ended April 20, at 10:30 a.m. ET.

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2. -- Facebook, Boeing, AMD Report Earnings

Comcast Corp. (CMCSA) reported first-quarter earnings of 62 cents a share, 3 cents ahead of estimates, and also said Wednesday that it has formalized its plans to take over Britain's Sky PLC with a bid that values Europe's biggest pay television group at more than $30 billion and challenges Rupert Murdoch's Twenty-First Century Fox Inc. (FOXA) .

Twitter Inc. (TWTR) posted first-quarter adjusted earnings of 16 cents a share, 4 cents ahead of estimates. Revenue was $655 million vs. estimates of $608 million. Twitter said monthly active users were 336 million, beating analysts' forecasts of 334.2 million. The stock rose 4.9% in premarket trading.

Boeing Co. (BA) earned $3.64 a share in the first quarter, higher than forecasts that called for $2.58. The aerospace maker also raised its 2018 forecast. The stock was up 1.9%.

Earnings reports are also expected Wednesday from Facebook Inc. (FB) , Advanced Micro Devices Inc. (AMD) , AT&T Inc. (T) , eBay Inc. (EBAY) , Ford Motor Co. (F) , Viacom Inc. (VIAB) , Chipotle Mexican Grill Inc. (CMG)  , Visa Inc. (V) and Qualcomm Inc. (QCOM) .

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3. -- Takeda Sweetens Bid for Shire

Shire PLC (SHPG) said it was willing to recommend a revised $64 billion offer from Takeda Pharmaceutical Co. (TKPYY)  after the U.K.-listed drugmaker rebuffed several other bids.

Shire said Wednesday that Takeda has offered 0.839 new Takeda shares and $30.33 in cash for each Shire ordinary share or about £49 a share. The offer breaks down to about £27.26 in new Takeda shares and £21.75 in cash and the sweetened deal values Shire at about £46 billion ($64 billion).

After the deal is completed, Shire shareholders would own about  50% of the enlarged Takeda and the new shares will be listed in Japan and in the U.S. through American depositary receipts.

4. -- Credit Suisse Posts a First-Quarter Beat

Credit Suisse Group AG  (CS)  jumped 4.2% in European trading after the Swiss investment bank posted its strongest quarterly earnings in three years as new cash poured into its wealth management division under the renewed focus of CEO Tidjane Thiam.

Credit Suisse said net profit for the three months ended in March hit Sfr694 million ($706.7 million), topping analysts' forecasts and rising 16.4% from the same period last year. The bank also said inflows into its wealth management division, a key growth driver, rose 20% to Sfr14.4 billion, the best in seven years, taking the total value of assets under management to Sfr776 billion.

The bank also reiterated its full-year profit targets but said it was too early to define its progress in the current quarter, owing to the recent market turmoil.

5. -- Texas Instruments Rises as Profit Jumps 37% 

Texas Instruments Inc. (TXN) was rising 3.8% in premarket trading on Wednesday after the chipmaker's profit in the first quarter jumped 37%.

The company reported first-quarter earnings of $1.37 billion, or $1.35 a share, which included 14 cents in tax-related benefits. A year earlier, Texas Instruments earned $997 million, or 97 cents a share. Revenue rose 11.4% to $3.79 billion as the chipmaker saw strong demand for its products in automotives and industrial markets.

Analysts were expecting TI to post a profit of $1.11 a share on revenue of $3.65 billion.

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