Vertex Pharmaceuticals (VRTX) - Get Report was up 1%. The Boston-based company on Wednesday reported fourth-quarter non-GAAP net income per share of 35 cents and total cystic fibrosis product net revenue of $454 million.

Shares of Neurocrine Biosciences (NBIX) - Get Report were up 2.9% in premarket trading on Friday. The San Diego-based company is a developer of treatments for neurological and endocrine-based diseases and disorders.

Aralez Pharmaceuticals (ARLZ) shares were down 3%. Aralez, whose global headquarters is in Mississauga, Ontario, is a pharmaceutical company focused on cardiovascular, pain and other specialty areas.