Shares of Organovo Holdings (ONVO) - Get Organovo Holdings, Inc. Report rose 8% to $2.83 in premarket trading on Thursday. The San Diego company develops three-dimensional human tissues for use in medical research and therapeutic applications. The company reported that Keith Murphy will step down as CEO effective April 21 and will be replaced by biotech veteran Taylor Crouch.

Meanwhile, shares of Endo International (ENDP) - Get Endo International Plc Report were up 6.1% to $11.20. Endo, whose global headquarters is in Dublin, Ireland and its U.S. headquarters is in Malvern, Pa., is a generics and specialty branded pharmaceutical company.

Other biotech movers include shares of Omeros (OMER) - Get Omeros Corporation Report . The stock is up 4.2% to $16.30. The Seattle-based firm focuses on small-molecule and protein therapeutics for large-market and orphan indications that target inflammation, coagulopathies and central nervous system disorders.

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