To stand still is to be disrupted, Jim Cramer told his Mad Money viewers Wednesday. That's why complacent companies quickly turn into dicey investments. Companies must always be reinventing themselves to stay relevant.

Cramer said nobody wants to invest in a sleepy old bank anymore, they want the red-hot financial tech companies like PayPal (PYPL) - Get Report and Square (SQ) - Get Report , along with both Visa (V) - Get Report and Mastercard (MA) - Get Report . All of these companies are quickly sending your checkbook into the history books.

In the advertising market, there are only three games left in town and they are Facebook (FB) - Get Report , Google (GOOGL) - Get Report and Amazon (AMZN) - Get Report .

Then there are the medical device makers, like Dexcom (DXCM) - Get Report and Tandem Diabetes (TNDM) - Get Report , which work together to create essentially an artificial pancreas for diabetes patients. Cramer said he thinks Apple (AAPL) - Get Report should acquire this pair of innovators.

Finally, Cramer said there's disruption in the orphan drug space, where new drugs replace old treatments with innovative ideas. That's why stocks like Regeneron (REGN) - Get Report have soared more than 2,000% over the past 10 years, and why you should have disruptors in your portfolio.

These are just a few of the reasons, Cramer said, he thinks Apple should get into healthcare and Kraft Heinz  (KHC) - Get Report should invest in cannabis companies.

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Executive Decision: Dell Technologies

For his "Executive Decision" segment, Cramer sat down with Michael Dell, chairman and CEO of Dell Technologies (DELL) - Get Report , the IT infrastructure company that is again publicly traded.

Dell explained that his company is now the leading IT infrastructure company, bringing together the best in storage with EMC, the best in servers with the old Dell and the best in virtualization software with VMWare (VMW) - Get Report . Dell currently owns 80% of VMware.

When it comes to infrastructure, especially in the cloud, Dell said his company services 99% of Fortune 500 companies and has 20,000 scientists and engineers working on research and development. The company has spent $20 billion on R&D thus far and is well positioned for the future.

Turning to the topic of artificial intelligence, Dell said that AI is meant to enable human potential and not leave swaths of society behind. He said it's important that creators of AI systems keep those goals in mind.

Finally, Dell talked about his charitable efforts, including the Michael and Susan Dell Foundation, which was instrumental in helping the city of Houston rebuild after Hurricane Harvey. The foundation created the Rebuild Texas fund and donated $36 million to the rebuilding effort. 

Retail Roundup 

There are many retailers that are having success with brick-and-mortar stores, Cramer told viewers, but TJX Companies (TJX) - Get Report , parent of TJ Maxx, Marshall's and HomeGoods, is certainly one of them.

Cramer explained that TJX is a discounter, which means the company buys up excess inventory from department stores, then sells it on the cheap to customers. This means TJX not only works in any economy, but it also makes the company immune to Amazon, as customers will always find a better price at TJ Maxx and Marshall's. The treasure-hunt experience of their stores makes finding these bargains even more enjoyable.

That's why Wall Street got it wrong this past November, when they sold TJX shares down from $56 to $49 before the company reported and down to lows near $41 a share by December. While TJX reported a good quarter, they also issued imperfect guidance, setting up an "UPOD" scenario of under-promising and over-delivering later on.

Unlike Burlington Stores (BURL) - Get Report , which did indeed have a disappointing quarter, Cramer said, TJX continues to do everything right, which is why he was a buying in November and December and would still be a buyer today. 

The Risk/Reward for Wells Fargo 

Wednesday was a rough day for Wells Fargo (WFC) - Get Report and its CEO, Tim Sloan, as the company was once again called to testify before Congress about its 2016 cross-selling scandal. But surprisingly, Wells Fargo's shares barely budged on the news, and Cramer thinks the risk/reward is starting to look pretty compelling.

There's a lot of pessimism still surrounding Wells Fargo, Cramer said, but it's been a full two years since the scandal first broke and Sloan has been hard at work cleaning up the company culture. Wells has already paid $185 million in fines for its transgressions.

Wells Fargo is again back on offense, Cramer added, delivering its highest earnings per share in its 166-year history. The bank's net interest margins are increasing, along with its overall efficiency.

Cramer said Well Fargo's shares may not yet be ready to rally, but they certainly have a lot less downside than many people think.

Cramer and the AAP team are looking at opportunities for growth in their portfolio. Find out what they're telling their investment club members and get in on the conversation with a free trial subscription to Action Alerts Plus.

Be Wary of Tech Gains

In his "No-Huddle Offense" segment, Cramer pondered whether investors are paying too much for Apple, Facebook and Alphabet, along with a host of other stocks that are rallying for seemingly no reason.

Cramer said there's been no real news to explain why shares of Apple have been rallying, except that the company is getting more in its earnings from services rather than cell phones. Facebook shares are also rising on little or no news. Then there's Alphabet. This company's core operations remain steady. Are investors revaluing the company's other businesses?

Cramer has never been a fan of multiple expansion, when investors are simply willing to pay more. He likes to see stock prices driven by increased sales and earnings. Right now, these stocks are rallying on hope, he said, and hope should never be part of your investing equation.

Lightning Round

In the Lightning Round, Cramer was bullish on Aphria (APHA) - Get Report , Barrick Gold (GOLD) - Get Report , Insperity (NSP) - Get Report , New Relic (NEWR) - Get Report and Edwards Lifesciences (EW) - Get Report .

Cramer was bearish on NovaGold Resources (NG) - Get Report .

On Real Money, Cramer keys in on the companies and CEOs he knows best. Get more of his insights with a free trial subscription to Real Money.

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At the time of publication, Cramer's Action Alerts PLUS had a position in FB, GOOGL, AMZN, AAPL.