Updated from 10:44 a.m. EDT

Shares of

Tractor Supply

(TSCO) - Get Report

were among

Nasdaq's

winners Wednesday, rising 10.2% after the retail farm and ranch store chain put first-quarter results above expectations and boosted its full-year guidance.

The company sees first-quarter earnings of $4 million to $5.1 million, or 10 cents to 12 cents a share. Analysts polled by Thomson First Call project break-even earnings. The company said that revenue came in at $559.8 million. Analysts expected $525.9 million.

Looking ahead, Tractor Supply now sees full-year earnings of $2.49 to $2.56 a share, up from an earlier view of $2.45 to $2.52 a share. It now projects revenue of $2.7 billion to $2.75 billion, up slightly from an earlier forecast of $2.7 billion to $2.74 billion. Analysts project earnings of $2.50 a share on revenue of $2.72 billion. Shares were trading up $5.19 to $56.30.

Alcoa

(AA) - Get Report

traded actively after the aluminum producer kicked off earnings season with better-than-expected first-quarter results. The company posted earnings from continuing operations of $691 million, or 79 cents a share, on revenue of $7.9 billion. Analysts expected earnings of 76 cents a share on revenue of $7.6 billion. During the year-earlier period, the company earned $615 million, or 70 cents a share, on revenue of $7.1 billion.

"Our focus on higher value-added solutions, such as aerospace products, and productivity programs helped to continue our momentum this quarter," the company said. Shares closed up 18 cents at $35.08.

Shares of

Chico's FAS

(CHS) - Get Report

got a boost after the clothing retailer posted solid March same-store sales. For the five weeks ended April 7, the Chico's posted an increase of 5.2% in same-store sales and a 22% jump in total sales. Total sales rose to $191.2 million from $156.8 million a year ago. Shares were trading up $1.86, or 7.4%, to $27.01.

Manor Care

( HCR), meanwhile, moved higher after the nursing-home operator said it is exploring strategic alternatives to boost shareholder value. The company said that it has retained JPMorgan to assist it in the process. "We are actively evaluating a full range of opportunities for further strengthening our strategic position and maximizing value for our shareholders," the company said. Shares were recently trading up $5.93, or 10.6%, to $61.68.

Western Refining

(WNR)

found itself on the losing side, after the company said the Federal Trade Commission is seeking to block its proposed merger with

Giant Industries

(GI)

. Western Refining said the FTC was acting "without basis in fact or law." As a result, the companies plan to "vigorously" challenge the FTC in court.

"The FTC's decision demonstrates a fundamental and troubling lack of understanding about the areas in which Western Refining and Giant operate, the competitors in those areas and the competitive nature of those areas," Western Refining said in a statement late Tuesday.

Shares of Western Refining were down $2.89, or 7.6%, to $34.97, while shares of Giant Industries were up $1.51, or 2.1%, to $73.39.

NYSE

volume leaders included

Freeport McMoRan

(FCX) - Get Report

, which was up 61 cents earlier in the day but closed down 53 cents to $69.93;

Ford

(F) - Get Report

, down 6 cents to $8.13;

Citigroup

(C) - Get Report

, down 60 cents to $51.80;

First Data

(FDC) - Get Report

, up 7 cents to $32.47;

Kraft Foods

( KFT), up 78 cents to $32.02; and

General Electric

(GE) - Get Report

, up 7 cents to $34.95.

Nasdaq volume leaders included

Cell Therapeutics

(CTIC) - Get Report

, up 21 cents to $1.83;

Intel

(INTC) - Get Report

, down 20 cents to $20.47;

Dendreon

(DNDN)

, down $3.92 to $18.23;

Sun Microsystems

(SUNW) - Get Report

, down 3 cents to $5.90;

Nuvelo

( NUVO), down 97 cents to $4.43;

Comcast

(CMCSA) - Get Report

, up71 cents to $27.42;

Microsoft

(MSFT) - Get Report

, down 29 cents to $28.11;

Cisco Systems

(CSCO) - Get Report

, down 20 cents to $25.79; and

Applied Materials

(AMAT) - Get Report

, down 18 cents to $19.23.