Trimeris( TRMS) surged in after-hours trading Tuesday as the Morrisville, N.C.-based biopharmaceutical company swung to a third-quarter profit.

The company reported income of $3.6 million, or 16 cents a share, compared with a loss of $3.3 million, or 15 cents a share. Revenue increased 114% to $9.7 million. Analysts polled by Thomson Financial were looking for earnings of 2 cents a share, on revenue of $8.8 million.

The company said the revenue increase was primarily helped by strong global sales of the anti-HIV drug Fuzeon, which reached $63 million, up 29% over a year ago. All sales of Fuzeon are recorded by

Hoffmann-La Roche

, Trimeris' collaborative partner. Shares were trading up $1.45, or 18.3%, to $9.38.

Air Methods

(AIRM)

gained as the Englewood, Colo.-based air medical transportation services and systems company saw third-quarter earnings increase 75%.

The company posted net income of $9.6 million, or 78 cents a share, up from$5.5 million, or 47 cents a share a year ago. Revenue increased 28% to $116.1 million. Two analysts polled by Thomson First Call were looking for earnings of 55 cents a share on $106.9 million in revenue. Shares were trading up $4.02, or 16.3%, to $28.64.

True Religion Apparel

(TRLG)

plummeted after the Los Angeles-based apparel company missed Wall Street's third-quarter expectations. The company posted income of $8.2 million, or 35 cents a share, compared with $7.73 million, or 33 cents a share, a year ago. Excluding items, the company reported income of $8.7 million, or 37 cents a share. Sales increased 22.6% to $42.9 million. Wall Street was looking for earnings of 44 cents a share on sales of $47.7 million.

Looking ahead, the company adjusted its expectation of sales for the full year to $138 million to $140 million, up 35% to 36% over last year. Excluding items, the company expects earnings in the range of $1.11 to $1.12 for 2006. Analysts are looking for $1.27 on revenue of $150 million. Shares were falling $4.26, or 20%, to $17.

Career Education

(CECO) - Get Report

climbed even though the Hoffman Estates, Ill.-based postsecondary education company reported a drop in third-quarter earnings. The company reported income of $20.7 million, or 22 cents a share, down from $54.9 million, or 53 cents a share, a year ago. Revenue fell 7% to $462.4 million. Analysts were looking for earnings of 29 cents a share on sales of $452 million.

"Although third-quarter results were disappointing, the board and management ... took a number of significant steps during the quarter to resolve our current issues, improve our operating results, and lay the foundation for future growth," Bob Dowdell, president and CEO, said in a statement. Shares were trading up $1.58, or 7.2%, to $23.44.

Youbet.com

( UBET) sank after the Woodland Hills, Calif.-based online-betting site swung to a third-quarter loss. The company posted a loss of $440,000, or 1 cent a share, compared with income of $1.8 million, or 5 cents a share, a year ago. Revenue rose about 42% to $37 million. Analysts were looking for earnings of 5 cents a share on sales of $39.7 million.

"Our third-quarter operating results reflect 9% year-over-year growth in online handle, which was less than we have achieved in recent quarters," Charles F. Champion, chairman and CEO, said in a statement.

"We believe this decline is related to the recruitment of high-volume U.S. customers by unlicensed bookmaking and sports betting operations that do not operate legally or contribute to the industry." Wall Street was looking for earnings of 5 cents a share on revenue of $39.7 million. Shares were falling 64 cents, or 15.3%, to $3.55.

National Semiconductor

(NSM)

slipped after the Santa Clara, Calif.-based chipmaker cut its revenue estimates for the current quarter, blaming slow sales to cell-phone makers. The company said that it now expects sales in its fiscal second quarter to decline 7% to 8% sequentially, instead of the 2%-5% decline it originally projected.

The warning marked the second quarter in a row that National Semi has had to trim its sales projections because of weaker-than-expected chip sales to cell-phone companies. In August, National Semi warned the Street that its fiscal first-quarter sales would be about $20 million less than its initial guidance.

On Tuesday, National Semi said decreasing foundry revenue from its divested cordless and PC super I/O business accounted for 4% of its sequential sales decline -- as the company had initially expected. But the chipmaker said lower-than-expected shipments to wireless handset customers were the primary reason for the extra 3%-4% of revenue decline, leading to its latest downward revision. Shares were falling 25 cents, or 1%, to $23.70.