Shares of heart-device developer

Vasogen

( VSGN) jumped after the company announced positive clinical-trial data at a cardiology meeting.

According to data presented at the World Congress of Cardiology meeting in Barcelona, Spain, a trial involving 2,400 patients with chronic heart failure showed that the company's Celacade technology reduced the risk of death and cardiovascular hospitalization by 31%. Shares were up 19.7% to 68 cents.

Applied Biosystems

(ABI)

was higher after the company reached a settlement with life-sciences company

Promega

resolving two legal disputes. Terms of the settlement were not disclosed. Shares were up 1.3% to $31.71.

Oscient Pharmaceuticals

(OSCI)

sank after the company announced an agreement with

Auxilium Pharmaceuticals

(AUXL)

to conclude a marketing partnership for the testosterone gel Testim.

According to the agreement, Oscient and Auxilium will share profits from sales through Aug. 31. Auxilium will pay Oscient $1.8 million in compensation for Oscient's salesforce efforts. Oscient fell 7.5% to $1.11, while Auxilium dipped 0.6% to $8.60.

German drug giant

Bayer

( BAY) slipped 1.2% to $48.92 after the company announced the expansion of the Shanghai production facilities at its chemicals subsidiary. The facilities will produce polycarbonate and polyurethane.

SkyePharma

( SKYE) declined despite an announcement Monday that the extended-release drug Requip delayed symptom recurrence in patients with Parkinson's disease. The extended release version of Requip, a

GlaxoSmithKline

(GSK) - Get Report

drug, was developed by SkyePharma using its proprietary controlled-release technology. Shares fell 1.7% to $4.70.

Among other stocks on the move were

Northfield Laboratories

( NFLD), whose shares dipped 1.3% to $10.58,

Avalon Pharmaceuticals

( AVRX), down 1.4% to $2.82, and

Sanofi-Aventis

(SNY) - Get Report

, off 1.5% to $44.67.

Progenics Pharmaceuticals

(PGNX) - Get Report

rose 12.5% to $25.50,

Nuvelo

( NUVO) was up 1.2% to $20.78, and

Accentia Biopharmaceuticals

(ABPI)

gained 2.6% to $3.09.