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Shares of

Affymetrix

(AFFX)

gained 12.5% after the bell rang Wednesday when the Santa Clara, Calif.-based company

swung to a loss but still beat Wall Street's third-quarter expectations.

The company, which makes systems for genetic analysis, posted a loss of $14.2 million, or 21 cents a share, compared with income of $9.4 million, or 14 cents a share a year ago. Excluding items, the company posted a loss 6 cents a share. Revenue totaled $84.7 million, with $4.6 million from the sale of its products to genomics company

Perlegen Sciences

. In the third quarter of 2005, the company reported revenue of $83.4 million, with $2.2 million from the sale of its products to Perlegen. Analysts polled by Thomson First Call were expecting the company to post a loss of 8 cents a share on revenue of $80.9 million. Shares were trading up $2.84, to $25.50.

Navteq

(NVT) - Get nVent Electric plc Report

advanced after the company beat third-quarter targets and

guided in line. The Chicago-based maker of navigation devices made $27 million, or 28 cents a share, for the quarter ended Oct. 1, down from the year-ago tax-benefit-padded $101 million, or $1.07 a share. Revenue rose to $143 million from $123 million a year earlier. Wall Street was looking for a 25-cent profit on sales of $140 million.

Navteq warned that this year's performance "is being negatively impacted by a number of factors, including unfavorable car sales trends in both Europe and North America, lower-than-expected revenue relating to portable devices in Europe and the collectibility of a customer receivable." As a result, Navteq expects to make $1.10 to $1.16 a share for the year on revenue of $565 million to $580 million. Analysts were looking for $1.12 a share on $576 million. Shares were trading up $3.05, or 10.5%, to $32.

Red Hat

( RHAT) plummeted after

Oracle

TheStreet Recommends

(ORCL) - Get Oracle Corporation Report

said it will offer full support for customers running Red Hat's version of the Linux operating system. Oracle CEO Larry Ellison

announced the new program at his company's OpenWorld convention. Ellison said Oracle will do a better job fixing bugs than Red Hat, indemnify customers against potential intellectual property issues, and offer better customer support for less money. Shares of Raleigh, N.C.-based Red Hat were tumbling $3.13, 16%, to $16.39.

F5

(FFIV) - Get F5 Networks, Inc. Report

soared after the networking company beat fiscal fourth-quarter revenue targets and

guided higher for the first quarter. The Seattle-based company said revenue for the quarter ended last month rose 12% sequentially and 39% from a year ago to $111.7 million. Analysts surveyed by Thomson Financial were looking for revenue of $105.5 million.

For the first quarter ending Dec. 31, the company expects revenue of $116 million to $118 million, against a $110 Thomson target. The company didn't report earnings because it is yet to complete a probe of apparent stock-option backdating. F5 said it will probably have to restate earnings going back to 1999 to the tune of $30 million in unrecognized stock-compensation costs. The company said it is continuing to cooperate fully with both the Department of Justice and the

Securities and Exchange Commission

in their respective inquiries regarding the company's historical stock-option practices. Shares were trading up $6.08, or 10.5%, to $64.20.

Bebe stores

(BEBE)

stumbled after the Brisbane, Calif.-based women's apparel and accessories company beat Wall Street's first-quarter expectations, but pulled up on its second-quarter guidance. The company posted net income of $20.4 million, or 22 cents a share, compared with $13.6 million, or 14 cents a share, a year ago. Sales increased 24.5% to $157.1 million. Same-store sales increased 12.8%. Wall Street was looking for the company to post income of 21 cents a share on revenue $156.6 million.

Looking ahead to the second quarter, the company said it is expecting earnings of 31 cents to 35 cents a share and same-store sales will be in the high single-digit range. Analysts are calling for income of 35 cents a share. Shares were trading down $3.59, or 13.4%, to $23.15.

Applebee's International

(APPB)

fell after the casual-restaurant chain posted a bigger-than-expected drop in third-quarter earnings and

cut its full-year profit outlook.

The Overland Park, Kan.-based company earned $14.8 million, or 20 cents a share, for the quarter ended Sept. 24, down from $22.1 million, or 28 cents a share, a year earlier. Excluding charges related to impairments and legal costs, but including 4 cents in stock-options expenses, earnings were 23 cents a share. Analysts polled by Thomson First Call anticipated earnings of 25 cents a share on this basis.

Revenue rose to $320.6 million from $305.3 million, while systemwide same-store sales declined 2.3%. Applebee's also reported a 1.2% same-store sales drop for its October fiscal period. The company expects systemwide same-store sales will fall 1% to 3% for the remainder of the year. Applebee's now sees earnings of $1.10 to $1.13 a share for the full year, excluding charges, but including options costs. That's down from its July forecast for earnings of $1.12 to $1.22 a share. Shares were falling $1.77, or 7.1%, or $23.10.