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Global uncertainty over issues in Iran, Iraq, Bombay and North Korea continued to move gold higher, sending shares in ETFs that track the precious metal up. The

streetTRACKS Gold Shares

(GLD) - Get Free Report

ETF rose 64 cents, or 1%, to $64.45. The

iShares COMEX Gold Trust

(IAU) - Get Free Report

ETF, meanwhile, advanced 50 cents, or 0.8%, to $64.49. Gold for August delivery touched as high as $657 an ounce on the New York Mercantile Exchange and was recently trading up $5.90 to $649.

The

Biotech HOLDRs Trust

(BBH) - Get Free Report

was down 1.2% following the earnings reports of two of its biggest components,

Genzyme

(GENZ)

and

Genentech

(DNA)

. Genzyme shares were higher by 8% after the company's earnings topped estimates. Genentech's profit also was above expectations, but shares were down 3.7% after sales of the cancer drug Avastin missed forecasts. The Biotech HOLDRs Trust recently was down $2.46 to $176.52.

The

Nasdaq 100 Trust

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slid 2% as some of its biggest holdings headed lower during late-afternoon trading.

Dell

(DELL) - Get Free Report

was recently down $1.05, or 4%, to $22.37.

Qualcomm

(QCOM) - Get Free Report

, meanwhile, fell $1.46, or 4%, to $37.41. And

Apple Computer

(AAPL) - Get Free Report

shed $2.08 to $53.57. The Nasdaq 100 ETF was trading down 65 cents to $36.99.

The

S&P Depository Receipts

(SPY) - Get Free Report

ETF fell 1% as

Intel

(INTC) - Get Free Report

,

Microsoft

(MSFT) - Get Free Report

and

IBM

(IBM) - Get Free Report

retreated Wednesday. Intel was recently trading down 55 cents, or 3%, to $18.12. Microsoft, which was fined $357 million by the European Union Commission on Wednesday for failing to comply with a 2004 antitrust settlement, slipped 42 cents, or 2%, to $22.68. Meanwhile, IBM lost $1.53, or 2%, after JPMorgan Chase cuts its revenue target for the computer maker. Shares in the S&P ETF were recently down $1.35 to $126.06.

Shares of

iShares Dow Jones U.S. Real Estate

(IYR) - Get Free Report

ETF rose modestly Wednesday as several of its component stocks traded higher.

Equity Office Properties Trust

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, which announced the acquisition of the Bertelsmann Building in New York City Wednesday morning, was recently trading up 38 cents to $37.61.

ProLogis

(PLD) - Get Free Report

, a real estate investment trust, was recently up 51 cents, or 1%, to $54.42. The real estate ETF was recently higher by 18 cents to $73.31.