Trial Results Lift Dynavax

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Dynavax (DVAX) - Get Report surged 23% late Tuesday after it reported what it called statistically significant results in a trial of its Heplisav hepatitis B virus vaccine.

The Berkeley, Calif., biotech said the results came in a primary endpoint analysis of a Phase 3 trial comparing Heplisav to


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Engerix-B vaccine in a difficult-to-immunize population of older adults. The primary endpoint is seroprotection four weeks after the third immunization, Dynavax said.

"These results once again demonstrate Heplisav's superior effectiveness over conventional hepatitis B vaccine," said CEO Dino Dina. "The most striking outcome from the trial is the vaccine's ability to generate 98.5% protection after two doses in older difficult-to-immunize adults. This has the potential to drive an important change in the way people are immunized against hepatitis B."

Shares rose $1.71 to $9.11.