The game, released on Sept. 13, sold 5 million copies in its first five days, the company said in a statement. The game is now Take-Two's bestselling title.
The Borderlands series has generated more than $1 billion in sales to date, making the game the second Take-Two franchise to cross that mark.
Wedbush Securities analyst Michael Pachter told Barron's that "overly optimistic investors may be disappointed by the initial numbers." The firm has an outperform rating and $144 price target on the company.
SunTrust analyst Matthew Thorton said the games' numbers were in line with Wall Street estimates.
Take-Two shares have jumped more than 20% year to date. Last month the company reported strong revenue and raised its guidance for the current quarter.
The stock is trading off 3.4% to $126.14.