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Did you miss last night's "Mad Money" on CNBC? If so, here are Jim Cramer's top takeaways for today's trading.

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TherapeuticsMD (TXMD) - Get TherapeuticsMD, Inc. Report : In an exclusive interview, Cramer sat down with Robert Finizio, CEO of TherapeuticsMD, the biotech working on hormone replacement therapies for women. Shares spiked 12.8% Tuesday on positive Phase III clinical data, but are still negative for the year.

Finizio explained there are two hormones that decline during menopause, and his company's drug is the first to formulate both of those drugs naturally. That's why he couldn't be happier the latest Phase III results show the formulation is both safe and effective.

Finizio added that the market opportunity in the U.S. alone could be $3.5 billion to $4.5 billion a year, with additional opportunities overseas. TherapeuticsMD plans to file for FDA approval in the third quarter of 2017, Finizio said, and after an expected 10-month review, bring the drug to market.

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Pioneer Natural Resources (PXD) - Get Pioneer Natural Resources Company Report : For his second interview, Cramer sat down with Scott Sheffield, chairman and CEO of Pioneer Natural Resources, the shale oil producer with shares up over 50% for the year, now that oil has surged past $50 a barrel.

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Sheffield is very bullish on Pioneer's assets, including the Permian Basin and in particular the Straberry/Wolfcamp shale, which he said is now the second largest oil field in the world. No one believed that three years ago, he noted, but now nearly half of U.S. oil rigs are located there.

Sheffield touted Pioneer's balance sheet, saying his company has no debt and the ability to growth without the need for additional equity offerings for quite some time to come.

As for operating costs, Sheffield said it now costs Pioneer just $8 to $10 a barrel in finding costs, which is down from $15 to $18 dollars just a few years ago. Those gains all stem from increased efficiency, which makes oil in the mid-$50s more than profitable.

Finally, Sheffield said that Pioneer received two Christmas presents in November, a deal from OPEC and Donald Trump, both of which make him excited for America and his industry's future.

With a stock up 400% under Sheffield's tenure, Cramer asked what's not to like about Pioneer Natural Resources?

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At the time of publication, Cramer's Action Alerts PLUS had no position in stocks mentioned.