Editor's Note: In this feature from Stockpickr, we highlight lists of stocks that have made new highs, lows or seen other unusual activity.

52-Week Highs:

Bausch & Lomb

( BOL) shares rose 9.8% to $67.50, a 52-week high, on news it agreed to be acquired by private-equity firm Warburg Pincus.

Biggest % Gainers:

Monolithic Power Systems

(MPWR) - Get Report

jumped 16% to $16.62, the day's biggest percentage gain. The semiconductor company benefited from a favorable verdict from a California jury in a patent infringement lawsuit.

The company also was

Rising on Unusual Volume. Shares were trading at more than nine times average.

Biggest % Losers:

Arrhythmia Research Technology

(HRT)

sank 35%, flat-lining with the day's biggest percentage drop. The company announced disappointing earnings Wednesday.

52-Week Lows:

Gaming Partners International

(GPIC) - Get Report

plummeted 32% to $10.83, a 52-week low. The gaming-chip manufacturer posted disappointing earnings.

Latest Activist Situations: Shamrock Activist Value Fund disclosed late on Tuesday that it had upped its stake to 6.37% in

Modine Manufacturing

(MOD) - Get Report

, which makes engine cooling components.

Forum of the day

Syntax-Brillian

( BRLC):

Sell or back up the truck? HazyDavy asks.

Do you know the answer?

Does Wachovia's downgrade of

Bear Stearns

( BSC) raise concerns for other banks, such as

Goldman Sachs

(GS) - Get Report

? windwardskies asks.

Feeling lucky?

And finally, try picking a random portfolio suited to do-it-yourselfers with more detailed analysis at

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