Shares of genome-medicine company Sangamo Therapeutics (SGMO - Get Report) surged Tuesday after the company nd Pfizer (PFE - Get Report) announced "encouraging" results from a phase 1-2 study of a gene therapy for the treatment of a severe type of hemophilia.
The company announced in a press release that its SB-525 developed with Pfizer was "generally well tolerated and demonstrated a dose-dependent increase in Factor VIII levels across the four dosage cohorts.
"These interim results suggest that SB-525 may be well-tolerated and may prove to have the predictability and sustained treatment effect that can bring clinical benefit in patients with hemophilia A," Sangamo Chief Medical Officer Edward Conner said in a statement.
Separately, Sangamo announced that early data for another gene-editing therapy called ST-400, developed in partnership with pharmaceutical company Sanofi, were also progressing well. It also provided an update on its AAV manufacturing capacity and capabilities.
Shares of Sangamo jumped 38.1% to $13.16 in trading Tuesday.
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