NEW YORK (TheStreet) -- Jim Cramer was asked via Twitter about financial stocks Wednesday, and he did not hesitate to say Wells Fargo (WFC) - Get Report, an Action Alerts PLUS holding, is the one financial stock you should own.

According to Cramer, Wells has the most leverage to when interest rates go up and has "been doing incredibly well." Stick with Wells Fargo over U.S. Bancorp (USB) - Get Report, even though U.S. Bancorp is also managed well, he advised.

In other questions from the floor of the New York Stock Exchange he was asked about Synchrony Financial (SYF) - Get Report, a spinoff of General Electric (GE) - Get Report, which the viewer bought in the mid-$20s. Shares are now around $33. Jim said the investor should continue to hold the stock.

On Fannie Mae (FNMA) , Cramer has ignored that stock because, he said, the U.S. Treasury Department says it's worthless. Cramer said financial stocks in general will continue to run higher until the Federal Reserveraises rates. After the rate hike, banks will start thinking about lending growth again, assuming the regulators "take their boot off the jugular of the banks."

On technology stocks, Cramer said Microsoft (MSFT) - Get Report is a buy at $45. He said the stock chart has broken down but disagrees with those who think the stock will go to $42 or $43. He pointed out Microsoft's last quarter was very good, and the company had a lot of cloud business, along with the Xbox.

He's not worried about semiconductor stocks and thinks Qualcomm (QCOM) - Get Reportshould buySkyworks (SWKS) - Get Report. He's focused on the role semiconductor companies will play in the Internet of Things, and likes Avago Technologies (AVGO) - Get Report, NXP Semiconductors (NXPI) - Get Report and Qorvo (QRVO) - Get Report.

Finally, on retail, Cramer said he likes VF Corp. (VFC) - Get Report and PVH (PVH) - Get Report but he's now thinking he prefers to be in Ralph Lauren (RL) - Get Report, which will benefit from the dollar falling against the euro.