Health stocks were bludgeoned on Wednesday, in line with the broader market, with the Nasdaq and Amex biotechnology indices down 4.2% and 4.5%, respectively.

Among individual stocks, notable movers were:

Orexigen

(OREX)

, up 24.2% at $5.55

Enzon

(ENZN)

, up 15.5% at $4.17

Senomyx

(SNMX)

, up 11.9% at $3.87

OSI Pharmaceuticals

( OSIP), up 5.7% at $37.31

NuVasive

(NUVA) - Get Report

, down 17% at $31.05

Savient

(SVNT)

, down 16% at $3.69

Amylin

( AMLN), down 13% at $6.28

AstraZeneca

(AZN) - Get Report

, down 11.5% at $37.14

Vertex

(VRTX) - Get Report

, down 10.7% at $23.50

Celera

( CRA), down 10.3% at $9.98

This article was written by a staff member of TheStreet.com.