Drug developer

SuperGen

( SUPG) was jumping 10% after Lazard Capital Markets upgraded the stock to hold from sell, based on valuation. Shares were adding 46 cents to $5.07.

UnitedHealth

(UNH) - Get Report

was also rising after the health insurer said it will be current with filings to the

Securities and Exchange Commission

on March 15. UnitedHealth was recently up $2.10, or 4%, at $54.84.

On the flipside,

Noven Pharmaceuticals

(NOVN) - Get Report

sank 10% even after the company posted fourth-quarter earnings that rose 18% from the year-ago period to beat estimates. Deutsche Securities downgraded the stock to hold from buy, and shares slipped $2.55 to $22.86.

Among healthcare winners Friday,

Affymetrix

(AFFX)

was rising 4.8% to $26.86.

NeoPharm

( NEOL) was higher by 3.9% to $2.09.

Nektar Therapeutics

(NKTR) - Get Report

was adding 2.1% at $11.96.

Among decliners,

Medarex

( MEDX) was off 3.5% at $12.41.

Sepracor

( SEPR) was losing 2.9% at $50.39.

Medicines Co.

(MDCO) - Get Report

was lower by 2.2% to $26.29.