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U.K. lawmakers voted for a third time to reject Prime Minister Theresa May's Withdrawal Agreement Friday, setting a path for Britain to leave the European Union without a bespoke deal on April 12.

May called the vote, which saw her defeat narrow to 58 votes from a prior count of 149 earlier this month, "a matter of profound regret." Opposition leader Jeremy Corbyn, as well as the Scottish National Party, urged her to call a general election to break the nation's crippling Brexit stalemate. Britain will have less than three weeks to either crash out of the EU without a bespoke arrangement or request a longer, perhaps multi-year deadline extension from Brussels.

"I think it should be a matter of profound regret to every member of this House that once again we have been unable to support leaving the European Union in an orderly fashion," May told lawmakers immediately following the vote. "The implications of the House's decision are grave."

"On Monday, this House will continue the process to see if there is a stable majority for a particular alternative version of our future relationship with the EU," she said. "This House has rejected no deal. It has rejected no Brexit. On Wednesday it rejected all the variations of the deal on the table. And today it has rejected approving the Withdrawal Agreement alone and continuing a process on the future."

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May is expected to hold a conference call on Sunday night with ministers, according to The Telegraph newspaper.

Following the news, the pound was marked 0.65% lower on the session at 1.2993 against the U.S dollar following the vote, falling below the 1.30 threshold for only the second time since February 18, before paring the decline to 1.3028.

May's Withdrawal Agreement, in essence, removes Britain from the EU but sets up a transition period during which talks on a future trading relationship will take place. Lawmakers have been reluctant to support it, however, as it has failed to satisfy those who wish to leave completely and sign new trade deals right away, as well as those who feel it cuts ties too quickly with Britain's biggest trading partner.

The key issue, however, is the treatment of the border between the Republic of Ireland, an EU member state, and Northern Ireland, a U.K. territory. Leaving the EU and its customs union would allow Britain to sign new trade agreements, but could also risk having a hard border between the two states that would violate terms of the Good Friday Peace Agreement signed in 1998.