"[Investor] focus is starting to shift away from fears around iOS changes towards a continued ad recovery and benefits from more e-commerce activity shifting into Facebook's platform," analyst Lloyd Walmsley said.
Deutsche Bank data checks show that advertisers have continued to spend on the platform in first-quarter 2021.
Zuckerberg noted that the Menlo Park, Calif., social-media provider now has 1 million active shops with 250 million users interacting with them on a monthly basis. For reference, Shopify (SHOP) - Get Report had more than 1.7 million global merchants at the end of 2020.
"We increase our first-quarter 2021 [excluding foreign exchange] ad-revenue growth to 31% (from 28.5% previously)," Walmsley said.
This outlook reflects "positive industry data, positive ad checks, the delay of iOS changes and recent optimism from Zuckerberg."
Facebook shares at last check were 2.6% higher at $290.28.