Don Dion's Weekly ETF Winners and Losers

Regional banks lead the way in ETFs this week.
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Leading the ETF pack this week were the regional banks. Though these institutions have been able to benefit as Washington continues its assault on Wall Street giants, speculation also played a part in these firms' rise over the past few days.

Winners

SPDR KBW Bank ETF

(KBE) - Get Report

+3.8%

iShares Dow Jones U.S. Regional Banks Index Fund

(IAT) - Get Report

+3.2%

SPDR KBW Regional Bank

(KRE) - Get Report

+2.1%

The U.K. financial goliath

Barclays

stirred up the regional banking sector on Wednesday when a report indicated that the firm was looking to acquire U.S. retail banking assets.

KBE saw an additional rise when Vikram Pandit of

Citigroup

(C) - Get Report

provided investors with an optimistic outlook for the troubled company. Citigroup accounts for 8% of the fund's index.

First Trust NYSE Arca Biotechnology Index Fund

(FBT) - Get Report

+4.5%

SPDR S&P Biotechnology

(XBI) - Get Report

+2.3%

PowerShares Dynamic Biotechnology and Genome Portfolio

(PBE) - Get Report

+2%

For the second week in a row, the biotech industry was a big winner in the ETF arena. As with last time, the FBT managed to handily beat its SPDR and iShares competitors to lead this health care subsector higher.

Helping to power FBT over XBI this week was

InterMune's

(ITMN)

60% jump on Wednesday

. In the past month alone, ITMN has managed to gain more than 120%. This week, the company saw a rise from the optimism that the FDA would approve its experimental drug used to treat idiopathic pulmonary fibrosis, a disease that causes scarring of the lung.

After the advance, InterMune is now FBT's top holding, accounting for more than 10% of the fund's total portfolio.

Market Vectors Indonesia

(IDX) - Get Report

+3%

Standard & Poor's raised Indonesia's foreign currency sovereign credit rating on Friday, and the nation's central bank raised growth estimates for 2010 and 2011. The country will be visited by President Obama later this month, and then by Chinese Prime Minister Wen Jiabao in April.

Though the fund is up 9.2% this year, it is still has about 1.5% to go before it surpasses its Jan. 19 high of $68.82.

Losers

United States Natural Gas Fund

(UNG) - Get Report

-4.6%

iPath Dow Jones-UBS Natural Gas Subindex Total Return ETN

(GAZ) - Get Report

-4.4%

United States 12 Month Natural

(UNL) - Get Report

-3.7%

UNG continues to set new records. The only problem for long investors is that those records are record lows. UNG broke $8 a share this week to close at $7.97. It was the first time the security traded below $8 intraday as well.

This week's slide came as inventory numbers met expectations. The decline in prices continues to be a healthy sign of natural gas supply, and investors will have to wait for a pickup in demand before UNG can put in a bottom.

iPath Dow Jones-UBS Grains Subindex Total Return ETN

(JJG) - Get Report

-2.4%

PowerShares DB Agriculture Fund

(DBA) - Get Report

-1.6%

Soybean, wheat and corn futures stumbled this week in light of strong forecast yields from top-producing nations including the U.S. and South America. As supplies continue to outweigh demand, expect commodity-backed agriculture funds like DBA to continue their underperformance.

iPath Dow Jones-UBS Nickel ETN

(JJN) - Get Report

-3.8%

Despite the continuation of a nearly seven-month mine strike in Subury, Ontario, nickel prices still faltered this week, and JJN led the losers.

Though this week's performance was dismal, global

nickel prices may soon see a rebound

. According to a report from UBS, global demand for the metal appears to be stabilizing, and producers in the developed world are beginning to ramp up production.

With the outlook for both demand and supply improving, the days of nickel's downfall may soon be numbered.

Don Dion is president and founder of

Dion Money Management

, a fee-based investment advisory firm to affluent individuals, families and nonprofit organizations, where he is responsible for setting investment policy, creating custom portfolios and overseeing the performance of client accounts. Founded in 1996 and based in Williamstown, Mass., Dion Money Management manages assets for clients in 49 states and 11 countries. Dion is a licensed attorney in Massachusetts and Maine and has more than 25 years' experience working in the financial markets, having founded and run two publicly traded companies before establishing Dion Money Management.

Dion also is publisher of the Fidelity Independent Adviser family of newsletters, which provides to a broad range of investors his commentary on the financial markets, with a specific emphasis on mutual funds and exchange-traded funds. With more than 100,000 subscribers in the U.S. and 29 other countries, Fidelity Independent Adviser publishes six monthly newsletters and three weekly newsletters. Its flagship publication, Fidelity Independent Adviser, has been published monthly for 11 years and reaches 40,000 subscribers.