DELAFIELD, Wis. (Stockpickr) -- Professional traders running mutual funds and hedge funds don't just look at a stock's price moves; they also track big changes in volume activity. Often when above-average volume moves into an equity, it precedes a large spike in volatility.

Major moves in volume can signal unusual activity, such as insider buying or selling -- or buying or selling by "superinvestors."

Unusual volume can also be a major signal that hedge funds and momentum traders are piling into a stock ahead of a catalyst. These types of traders like to get in well before a large spike, so it's always a smart move to monitor unusual volume. That said, remember to combine trend and price action with unusual volume. Put them all together to help you decipher the next big trend for any stock.

With that in mind, let's take a look at several stocks rising on unusual volume recently.

La Jolla Pharmaceutical

La Jolla Pharmaceutical (LJPC) - Get Report , a biopharmaceutical company, focuses on the discovery, development and commercialization of therapeutics for chronic organ failure and cancer. This stock closed up 10.2% to $11.25 in Friday's trading session.

Friday's Volume: 369,000
Three-Month Average Volume: 150,552
Volume % Change: 216%

From a technical perspective, LJPC exploded sharply higher here with above-average volume. This large move to the upside on Friday pushed shares of LJPC into breakout territory, since the stock took out some near-term overhead resistance levels at $10.43 to $11.24. Shares of LJPC are now quickly moving within range of triggering another big breakout trade. That trade will hit if LJPC manages to take out Friday's intraday high of $11.48 to some past overhead resistance at $12.25 with high volume.

Traders should now look for long-biased trades in LJPC as long as it's trending above Friday's intraday low of $10.45 and then once it sustains a move or close above $11.48 to $12.25 with volume that hits near or above 150,552 shares. If that breakout begins soon, then LJPC will set up to re-test or possibly take out its next major overhead resistance levels at $13.51 to $16.22.

IPC The Hospitalist Company

IPC The Hospitalist Company (IPCM) , through its subsidiaries, provides hospitalist services in the U.S. This stock closed up 1.9% at $40.07 in Friday's trading session.

Friday's Volume: 499,000
Three-Month Average Volume: 147,317
Volume % Change: 259%

From a technical perspective, IPCM trended modestly higher here with above-average volume. This stock recently gapped down sharply from around $47 to its new 52-week low of $36.12 with monster downside volume. Following that move, shares of IPCM have started to rebound sharply higher off that $36.12 low and have broken out back into that previous gap-down-day zone. Market players should now look for a continuation move to the upside in the short-term if IPCM manages to take out Friday's intraday high of $40.50 with high volume.

Traders should now look for long-biased trades in IPCM as long as it's trending above Friday's intraday low of $39.28 and then once it sustains a move or close above Friday's intraday high of $40.50 with volume that hits near or above 147,317 shares. If that move develops soon, then IPCM will set up to re-fill some more of its previous gap-down-day zone that started near $47.

Carlisle Companies

Carlisle Companies (CSL) - Get Report operates as a diversified manufacturing company in the U.S. and internationally. This stock closed up 0.8% to $85.68 in Friday's trading session.

Friday's Volume: 2.38 million
Three-Month Average Volume: 361,438
Volume % Change: 641%

From a technical perspective, CSL trended modestly higher here with monster upside volume. This stock recently gapped up sharply higher from around $78 to $86.28 with decent upside volume flows. This spike to the upside on Friday is now quickly pushing shares of CSL within range of triggering a major breakout trade. That trade will hit if CSL manages to take out some near-term overhead resistance at $86.28 to its 52-week high at $88.36 with high volume.

Traders should now look for long-biased trades in CSL as long as it's trending above some key near-term support levels at $84 or at $83 and then once it sustains a move or close above those breakout levels with volume that hits near or above 361,438 shares. If that breakout hits soon, then CSL will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $95 to $100.

Susser Petroleum Partners

Susser Petroleum Partners (SUSP) is engaged in the wholesale distribution of motor fuels primarily in Texas, New Mexico, Oklahoma and Louisiana. This stock closed up 1.5% at $46 in Friday's trading session.

Friday's Volume: 551,000
Three-Month Average Volume: 206,117
Volume % Change: 239%

From a technical perspective, SUSP trended modestly higher here right above some near-term support at $44.13 and above its 200-day moving average of $43.85 with strong upside volume flows. This small bump to the upside on Friday is starting to push shares of SUSP within range of triggering a near-term breakout trade. That trade will hit if SUSP manages to take out some near-term overhead resistance levels at Friday's intraday high of $46.19 to some more resistance at $47.39 with high volume.

Traders should now look for long-biased trades in SUSP as long as it's trending above its 200-day at $43.85 and then once it sustains a move or close above those breakout levels with volume that hits near or above 206,117 shares. If that breakout kicks off soon, then SUSP will set up to re-fill some of its previous gap-down-day zone from a few trading sessions ago that started near $51. Any high-volume move above $51.11 to its 50-day at $52.76 will then give SUSP a chance to tag its next major overhead resistance level at $56.

Eagle Bancorp

Eagle Bancorp (EGBN) - Get Report   operates as a bank holding company for EagleBank that provides commercial and consumer banking services in the U.S. This stock closed up 1.8% at $33.73 in Friday's trading session.

Friday's Volume: 235,460
Three-Month Average Volume: 69,665
Volume % Change: 251%

From a technical perspective, EGBN spiked modestly higher here back above both its 50-day moving average of $33.09 and its 200-day moving average of $33.49 with strong upside volume flows. This move to the upside on Friday is now starting to push shares of EGBN within range of triggering a big breakout trade. That trade will hit if EGBN manages to take out some key near-term overhead resistance levels at $34.63 to $35.13 and then above $35.48 with high volume.

Traders should now look for long-biased trades in EGBN as long as it's trending above some key near-term support at $32 and then once it sustains a move or close above those breakout levels with volume that's near or above 69,665 shares. If that breakout develops soon, the EGBN will set up to re-test or possibly take out its 52-week high at $37. Any high-volume move above that level will then give EGBN a chance to tag or take out $40.

To see more stocks rising on unusual volume, check out the Stocks Rising on Unusual Volume portfolio on Stockpickr.

-- Written by Roberto Pedone in Delafield, Wis.

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At the time of publication, author had no positions in stocks mentioned. Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.