DELAFIELD, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside.

Exelixis

Exelixis (EXEL) - Get Report , a biopharmaceutical company, develops small molecule therapies for the treatment of cancer in the U.S. This stock is trading up 7.6% to $2.04 in Tuesday's trading session.

Tuesday's Range: $1.89-$2.04
52-Week Range: $1.26-$7.58
Tuesday's Volume: 1.21 million
Three-Month Average Volume: 2.76 million

From a technical perspective, EXEL is ripping sharply higher here right above some near-term support at $1.80 with decent upside volume flows. This stock has been uptrending strong over the last month and change, with shares moving higher from its low of $1.26 to its recent high of $2.11. During that uptrend, shares of EXEL have been making mostly higher lows and higher highs, which is bullish technical price action. This sharp jump to the upside on Tuesday is now quickly pushing shares of EXEL within range of triggering a major breakout trade. That trade will hit if EXEL manages to clear some key near-term overhead resistance at $2.11 with high volume.

Traders should now look for long-biased trades in EXEL as long as it's trending above some key near-term support at $1.80 and then once it sustains a move or close above $2.11 with volume that hits near or above 2.76 million shares. If that breakout triggers soon, then EXEL will set up to re-fill some of its previous gap-down-day zone from last September that started just above $4 a share.

MEI Pharma

MEI Pharma (MEIP) - Get Report , an oncology company, focuses on the clinical development of novel therapies for the treatment of cancer. This stock is trading up 2.8% to $4.28 in Tuesday's trading session.

Tuesday's Range: $4.16-$4.44
52-Week Range: $3.57-$13.98
Tuesday's Volume: 384,000
Three-Month Average Volume: 349,463

From a technical perspective, MEIP is spiking notably higher here right above some near-term support at around $4 with strong upside volume flows. This stock recently formed a double bottom chart pattern at $3.57 to $3.61. Following that bottom, shares of MEIP have started to uptrend with the stock moving higher from that $3.57 low to its intraday high of $4.44. During that uptrend, shares of MEIP have been consistently making higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of MEIP within range of triggering a big breakout trade. That trade will hit if MEIP manages to take out some key near-term overhead resistance levels at its 50-day moving average of $4.42 and then above $4.63 with high volume.

Traders should now look for long-biased trades in MEIP as long as it's trending above $4 or above those double bottom support levels and then once it sustains a move or close above those breakout levels with volume that hits near or above 349,463 shares. If that breakout materializes soon, then MEIP will set up to re-test or possibly take out its next major overhead resistance levels at $5 to $5.50, or even $6.

Amarin

Amarin (AMRN) - Get Report , a biopharmaceutical company, focuses on the development and commercialization therapeutic products for the treatment for cardiovascular diseases in the U.S. This stock is trading up 2.6% to $1.14 in Tuesday's trading session.

Tuesday's Range: $1.11-$1.18
52-Week Range: $0.78-$2.09
Tuesday's Volume: 1.51 million
Three-Month Average Volume: 1.56 million

From a technical perspective, AMRN is spiking notably higher here with strong upside volume flows. This spike to the upside on Tuesday has briefly pushed shares of AMRN into breakout territory, since this stock has flirted with some key near-term overhead resistance at $1.15. Shares of AMRN are now quickly moving within range of triggering a much bigger breakout trade above some key overhead resistance levels. That trade will hit if AMRN manages to take out some near-term overhead resistance levels at Tuesday's intraday high of $1.18 and then above $1.20 with high volume.

Traders should now look for long-biased trades in AMRN as long as it's trending above its 50-day at $1.06 or above more key near-term support levels at 98 to 93 cents per share and then once it sustains a move or close above those breakout levels with volume that registers near or above 1.56 million shares. If that breakout develops soon, then AMRN will set up to re-test or possibly take out its next major overhead resistance levels at $1.32 to its 200-day moving average of $1.34, or $1.38. Any high-volume move above $1.38 and then over $1.50 will give AMRN a chance to re-fill some of its previous gap-down-day zone from last September that started near $2.

Amicus Therapeutics

Amicus Therapeutics (FOLD) - Get Report , a biopharmaceutical company, focuses on the discovery, development and commercialization of medicines for various rare and orphan diseases. This stock is trading up 8.5% to $7.74 a share in Tuesday's trading session.

Tuesday's Range: $7.26-$7.78
52-Week Range: $1.77-$9.63
Tuesday's Volume: 676,000
Three-Month Average Volume: 1.86 million

From a technical perspective, FOLD is ripping sharply higher here right above some near-term support at $7 with decent upside volume flows. This stock recently formed a double bottom chart pattern at $6.80 to $6.89. Following that bottom, shares of FOLD have started to spike sharply higher and it's now quickly moving within range of triggering a major breakout trade. That trade will hit if FOLD manages to take out some key near-term overhead resistance levels at $7.72 to its 50-day moving average of $8.08 and then above more resistance at $8.37 with high volume.

Traders should now look for long-biased trades in FOLD as long as it's trending above those double bottom support levels and then once it sustains a move or close above those breakout levels with volume that registers near or above 1.86 million shares. If that breakout gets underway soon, then FOLD will set up to re-test or possibly take out its next major overhead resistance levels at $9 to its 52-week high of $9.63. Any high-volume move above $9.63 will then give FOLD a chance to tag or take out $10 a share.

-- Written by Roberto Pedone in Delafield, Wis.

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At the time of publication, author had no positions in stocks mentioned. Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.