Vertex Pharmaceuticals (VRTX) Stock Falls Today on Cystic Fibrosis Drug Trial Data

Shares of Vertex Pharmaceuticals (VRTX) were down in morning trading Monday after the company announced its cystic fibrosis drug Kalydeco came up short of analysts' expectations in a mid-stage trial.
By Andrew Meola ,

NEW YORK (TheStreet) -- Shares of Vertex Pharmaceuticals  (VRTX) - Get Report fell 4.66% to $124.90 in morning trading Monday after the company announced its cystic fibrosis drug Kalydeco came up short of analysts' expectations in a mid-stage trial.

Patients who took Kalydeco, also known as ivacaftor, in combination with Vertex's VX-661 experimental drug experienced a 4.4% increase in the amount of air they could exhale in 1 second. This measurement assesses a patient's pulmonary function.

A survey by Evercore ISI, however, noted that analysts on average expected a 6% increase.

"The safety and efficacy data from this study are consistent with prior Phase 2 studies of VX-661 in combination with ivacaftor and provide further support for our ongoing Phase 3 program in people with one or two copies of the F508del mutation," said Jeffrey Chodakewitz, M.D., Executive Vice President and Chief Medical Officer at Vertex, in a statement.

VRTX data by YCharts

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