Tensions in the Ukraine affect Asia and early trading in Europe, but pharmaceuticals focus drives all main markets up and even reverses the morning's decline in Moscow. AstraZeneca biggest riser in London as Pfizer says still keen on a takeover, which it valued at $100 billion in an earlier approach in January. Germany's Bayer also pulled up the market there with talk of a sale of its plastics division to concentrate on pharmaceuticals. Siemens could pit itself against General Electric in race for French engineer Alstom. Asia concerned about geopolitics and Fed taper.