Wednesday's Winners & Losers: Buffalo Wild Wings

Shares of Garmin(GRMN Quote) plunged $5.54, or 11.9%, to $40.90 after the GPS-systems based navigation devices maker missed analysts' first-quarter earnings targets amid what it said is a slowdown in the global economy. Garmin reported net income of $147.8 million vs. $139.9 million a year ago. Excluding items, profit was up to 69 cents a share from 59 cents the year before but fell short of analysts' estimates of 75 cents a share. Revenue for the first quarter jumped 35% to $664 million but was down 45.6% sequentially and came in lower than Wall Street's estimates of $705 million.

Biotech BioMarin Pharmauceutical (BMRN Quote) said Tuesday post-close that it swung to a profit of $1.7 million, or 2 cents a share, vs. a loss of $9.3 million, or 10 cents a share, in the year-ago quarter. Higher sales and collaboration gains helped push revenue to $60.4 million, from $22.8 million in the 2007 period.

Analysts, on average, had expected a loss of 5 cents a share on revenue of $55.7 million. Shares were up $7.6% to $36.33. ...