Idenix Pharma to Cut Tyzeka, Jobs

Idenix Pharmaceuticals(IDIX Quote) is restructuring to focus on hepatitis C virus (HCV) and HIV programs, a move that involves discontinuing all activities for hepatitis B treatment Tyzeka and cutting a third of its workforce. The plan, announced just before the market open Friday, will result in estimated annual savings of $40 million to $45 million.

The company amended its agreement with Novartis(NVS Quote) regarding HBV treatment Tyzeka and now has no development, manufacturing or commercial activities for the drug, but will receive a royalty on worldwide sales. Subsequent to the discontinuation of its role in Tyzeka, Idenix is laying off around 100 positions, or roughly a third of the company.

Idenix expects to incur between $5 million and $10 million in charges, mostly associated with one-time employee severance benefits and the write-off of certain assets. ...