Wednesday's ETF Winners & Losers

Global uncertainty over issues in Iran, Iraq, Bombay and North Korea continued to move gold higher, sending shares in ETFs that track the precious metal up. The streetTRACKS Gold Shares(GLD Quote) ETF rose 64 cents, or 1%, to $64.45. The iShares COMEX Gold Trust(IAU Quote) ETF, meanwhile, advanced 50 cents, or 0.8%, to $64.49. Gold for August delivery touched as high as $657 an ounce on the New York Mercantile Exchange and was recently trading up $5.90 to $649.

The Biotech HOLDRs Trust (BBH Quote) was down 1.2% following the earnings reports of two of its biggest components, Genzyme (GENZ Quote) and Genentech(DNA Quote). Genzyme shares were higher by 8% after the company's earnings topped estimates. Genentech's profit also was above expectations, but shares were down 3.7% after sales of the cancer drug Avastin missed forecasts. The Biotech HOLDRs Trust recently was down $2.46 to $176.52.

The Nasdaq 100 Trust(QQQQ Quote) slid 2% as some of its biggest holdings headed lower during late-afternoon trading. Dell(DELL Quote) was recently down $1.05, or 4%, to $22.37. Qualcomm(QCOM Quote), meanwhile, fell $1.46, or 4%, to $37.41. And Apple Computer(AAPL Quote) shed $2.08 to $53.57. The Nasdaq 100 ETF was trading down 65 cents to $36.99. ...