This Day On The Street
Continue to site
This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here

Pfizer Announces Over 10 Abstracts For XELJANZ® (Tofacitinib Citrate) In Rheumatoid Arthritis To Be Presented At The European League Against Rheumatism (EULAR) 2014 Annual Meeting

Pfizer Inc. announced today that over 10 abstracts have been accepted for presentation at the European League Against Rheumatism (EULAR) 2014 Annual Meeting (June 11-14, Paris, France), seven of which are focused on further characterizing the safety profile of XELJANZ (tofacitinib citrate) in treating moderately to severely active rheumatoid arthritis. Notably, an abstract titled, “Integrated safety analysis of tofacitinib in rheumatoid arthritis clinical trials with a cumulative exposure of 12,664 patient-years,” will be presented as an oral abstract session (OP0154) on June 13, 2014 at 11:30 a.m. CEST. This analysis describes safety data for XELJANZ in patients from the integrated rheumatoid arthritis clinical trial database, which is based on cumulative exposure in Phase 2, Phase 3, and open-label long-term extension studies. The analysis includes 5,671 patients with a median exposure of 2.4 years including more than 500 patients followed for greater than four years.

“Pfizer is proud to showcase our commitment to the ongoing study of XELJANZ, with a focus on further establishing its benefit:risk profile in rheumatoid arthritis, a disease which affects more than 23 million people worldwide,” said Dr. Steven Romano, Global Medicines Development Lead for the Pfizer Global Innovative Pharmaceutical business.

XELJANZ is now approved in more than 20 countries for the treatment of patients with moderately to severely active rheumatoid arthritis who had an inadequate response to existing therapies. Most recently, Health Canada approved XELJANZ 5 mg twice daily in combination with methotrexate for reducing the signs and symptoms of rheumatoid arthritis in adult patients with moderately to severely active rheumatoid arthritis who have had an inadequate response or intolerance to methotrexate. In cases of intolerance to methotrexate, physicians may consider the use of XELJANZ as monotherapy. Regulatory applications for XELJANZ for the treatment of moderately to severely active rheumatoid arthritis remain under review in more than 35 additional countries. In Europe, XELJANZ is approved in Russia, Switzerland and Turkey, and Pfizer is working on next steps to re-file an application with the European Medicines Agency (EMA).

1 of 4

Check Out Our Best Services for Investors

Action Alerts PLUS

Portfolio Manager Jim Cramer and Director of Research Jack Mohr reveal their investment tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
Quant Ratings

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
Stocks Under $10

David Peltier uncovers low dollar stocks with serious upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
14-Days Free
Only $9.95
14-Days Free
Dividend Stock Advisor

David Peltier identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Updates with exact steps to take - BUY, HOLD, SELL
Trifecta Stocks

Every recommendation goes through 3 layers of intense scrutiny—quantitative, fundamental and technical analysis—to maximize profit potential and minimize risk.

Product Features:
  • Model Portfolio
  • Intra Day Trade alerts
  • Access to Quant Ratings
Real Money

More than 30 investing pros with skin in the game give you actionable insight and investment ideas.

Product Features:
  • Access to Jim Cramer's daily blog
  • Intraday commentary and news
  • Real-time trading forums
Only $49.95
14-Days Free
14-Days Free


Chart of I:DJI
DOW 17,798.49 -14.90 -0.08%
S&P 500 2,090.11 +1.24 0.06%
NASDAQ 5,127.5250 +11.3820 0.22%

Free Reports

Top Rated Stocks Top Rated Funds Top Rated ETFs