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Watch AstraZeneca, Pfizer, Sarepta and Hasbro Today: StockTwits

NEW YORK (TheStreet) -- It's going to be a big day in the markets, especially for these top-trending companies on StockTwits.

1. Sarepta Therapeutics (SRPT - Get Report) shares are surging nearly 60% this morning amid news of plans to submit an application for a new drug.

Sarepta $SRPT Plans to Submit NDA for Eteplirsen by End of 2014

-- StreetInsider (@Street_Insider) Apr. 21 at 05:05 AM

2. Word on the street is that AstraZeneca (AZN - Get Report) is in play and Pfizer (PFE) has extended a buyout offer in the neighborhood of $100 million. Shares of AZN are up over 5% in premarket as players digest the industry ramifications:

$PFE has put forward a bid of $100 billion for $AZN, according to a report published by London-based Sunday Times

-- Bidness Etc (@BidnessEtc) Apr. 21 at 07:10 AM

3. Several stocks are out with earnings this morning, and early trading action might be volatile: Hasbro (HAS), Kimberley Clark (KMB), Lennox International (LII), Bank of Hawaii (BOH), Chemical Financial (CHFC), Tennant (TNC), NVR (NVR), Washington Trust Bancorp (WASH) and Synalloy (SYNL).

$HAS kicks things off with an EPS beat

-- Derald Muniz (@1nvestor) Apr. 21 at 04:42 AM

Kimberly-Clark $KMB Q1 Adj. EPS USD 1.41 vs. Exp. USD 1.47

-- FinancialJuice (@FinancialJuice) Apr. 21 at 05:30 AM

Halliburton $HAL beats eps by a penny. Revenues by $600m. Not a blow out like $BHI. Could see a fade like $SLB.

-- Elam Rajaguru (@bigelam) Apr. 21 at 05:35 AM

Follow me on StockTwits: @chicagosean

At the time of publication, the author held no positions in any of the stocks mentioned.

This article represents the opinion of a contributor and not necessarily that of TheStreet or its editorial staff.

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