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Curis Announces Presentation Of Data For CUDC-907, CUDC-427 And Debio 0932 At AACR Annual Meeting

LEXINGTON, Mass., March 31, 2014 (GLOBE NEWSWIRE) -- Curis, Inc. (Nasdaq:CRIS), an oncology-focused company developing novel, targeted drug candidates for the treatment of human cancers, today announced that Curis scientists and collaborators will present data from three programs at the Annual Meeting of American Association for Cancer Research (AACR) to be held from April 5 th to 9 th in San Diego, CA. Curis researchers will present data for two of its proprietary targeted cancer drug candidates, CUDC-907, a dual HDAC and PI3K inhibitor and CUDC-427, an antagonist of IAP proteins.

Curis' partner Debiopharm will present data for Debio 0932, an orally-administered heat shock protein (HSP90) inhibitor.

Additional information on the presentations can be found below and abstracts can be accessed at .
Poster Presentations:
Date/Time: Sunday, April 6, 2014, 1:00 PM - 5:00 PM
Location: Hall A-E, Poster Section 37
Session Title:  Predictive Biomarker 1
Session Category: Clinical Research 2
Presentation Title: Post-treatment changes in levels of TNF family ligands and XIAP may predict sensitivity to IAP antagonist CUDC-427
Abstract Number: 917
Date/Time:  Monday, April 7, 2014, 8:00 AM - 12:00 PM
Location:  Hall A-E, Poster Section 37 
Session Title:  New Diagnostics, Therapeutic Targeting, and Response Assessments
Session Category: Clinical Research 5
Presentation Title: Dual function HDAC and PI3K inhibitor, CUDC-907 affects cancer cells and the tumor microenvironment in hematological malignancies
Abstract Number: 1879
Date/Time:  Monday, April 7, 2014, 8:00 AM - 12:00 PM
Location:  Hall A-E, Poster Section 33
Session Title:  Novel Targets 1
Session Category: Experimental and Molecular Therapeutics 14
Presentation Title: Identification of synergistic drug combinations with the oral HSP90 inhibitor Debio 0932 in non-small cell lung cancer and renal cell cancer
Abstract Number: 1792

About Curis, Inc.

Curis is an oncology-focused drug development company seeking to develop novel drug candidates for the treatment of human cancers. Curis is seeking to further the development of its pipeline of proprietary targeted cancer drug candidates, including CUDC-907, a dual HDAC and PI3K inhibitor and CUDC-427, a small molecule antagonist of IAP proteins. Erivedge® is our most advanced asset and the first and only FDA-approved medicine for the treatment of advanced basal cell carcinoma and is being commercialized and developed by Roche and Genentech, a member of the Roche Group, under a collaboration agreement between Curis and Genentech.  Curis-discovered HSP90 inhibitor, Debio 0932 is being studied in patients with advanced lung and kidney cancers by partner Debiopharm. For more information, visit Curis' website at .
CONTACT: For More Information:
         Mani Mohindru, Ph.D.
         Vice President, Corporate Strategy and Investor Relations
         Curis, Inc.
         Michael P. Gray
         Chief Financial and Chief Business Officer
         Curis, Inc.

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