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Waters Marks Ten Years Of ACQUITY UPLC; Looks To Future With ACQUITY QDa And IonKey/MS At Pittcon

CHICAGO, March 3, 2014 /PRNewswire/ -- Waters ® Corporation (NYSE: WAT) today celebrated the ten-year anniversary of the ACQUITY® UltraPerformance LC® (UPLC®) System, a technology that created a new industry standard for chromatographic performance.   Looking forward, Waters today also introduced the new ionKey/MS™ System, a new approach for getting exceptional sensitivity, robustness and ease-of-use out of mass spectrometry and featured the ACQUITY QDa™, the first mass detector to bring high-quality, mass spectral data to chromatographic separations, in its Pittcon debut.
Waters Corporation.

"In 2004, we changed the game. High Performance Liquid Chromatography (HPLC) wasn't keeping pace with business demands to analyze more samples, faster and with better results. The introduction of ACQUITY UPLC in 2004 transformed laboratory science and the analytical science industry," said Art Caputo, President of the Waters Division.

Over the last ten years, ACQUITY UPLC has had a profound effect on laboratories worldwide, both scientifically as well as from a business standpoint.  The novel ability of the ACQUITY UPLC to perform separations on 1.7 micron particle technology coupled with the ability to operate at 15,000 psi, opened new possibilities for analytical testing. The narrow, more concentrated peaks of ACQUITY UPLC improved ionization efficiency. Enhanced resolution and robustness led to high-quality, reproducible analysis in significantly less time, reducing run times by up to a factor of 10 compared to HPLC technology.  Through this increased productivity, it has been shown time and again that one ACQUITY UPLC system typically displaces multiple HPLC instruments.

ACQUITY UPLC has also proven to be a sustainable solution for laboratories; saving energy, using less solvent and producing less waste.  Again, in comparison to HPLC technology, laboratories utilizing ACQUITY UPLC save approximately 222 liters of solvent per year. Over a ten-year period that equates to 5.5 million liters of solvent, which represents a cost savings of over a HALF BILLION USD to Waters' customers.

ionKey/MS System Redefines MS Performance

The new ionKey/MS™ System, a new approach for getting exceptional sensitivity, robustness and ease-of-use out of mass spectrometry for applications as far-ranging as bioanalyses and pharmacokinetic studies to food safety and environmental analyses. Intended for use with Waters ACQUITY UPLC M-Class System and Xevo® TQ-S Mass Spectrometer, the Waters ionKey/MS System physically integrates a UPLC separation into the mass spectrometer producing a significant improvement in sensitivity, enabling scientists to achieve unparalleled separation and detection of compounds. Waters introduced the ionKey/MS System at the Pittcon Conference and Exposition March 2 – 6. Waters is making the ionKey/MS System immediately available to scientists on a worldwide basis.

"ionKey/MS will change how the world thinks about LC/MS. With ionKey/MS we are enabling any scientist to operate the most sensitive LC/MS analysis on the market, eliminating many variables and simplifying the user experience," said Ian King, Ph.D., Vice President, Separations Technology, Waters Division. "This can have a big impact by reducing training requirements and standardizing operations.  With the ionKey/MS System we have made it possible for scientists to reduce solvent and sample sizes. This results in more environmentally, ethically and economically –sound operation by lowering costs and solvent waste and reducing the amount of sample needed for analysis."

In addition to the enhanced sensitivity, scientists praise the plug and play nature of ionKey/MS. Scientists no longer have to contend with delicate fittings and columns and concern themselves with extra column dispersion and the inevitable variability and band broadening that comes with it. The ionKey/MS System's iKey Microfluidic Separation Device is designed so that all it takes is a few seconds for a scientist to insert it into the source of the mass spectrometer and with the turn of a key, make the fluidic and electric connections and lock it into place.

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