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Waters Introduces UPLC System For Nano- To Microscale Separations - The ACQUITY UPLC M-Class System

MILFORD, Mass., Jan. 28, 2014 /PRNewswire/ -- Waters Corporation (WAT:NYSE) today introduced the new Waters® ACQUITY UPLC® M-Class System, an industry-first nano- to microscale UltraPerformance LC ® (UPLC ®) system rated for 15,000 psi operation. Coupled to Waters mass spectrometers, the system delivers the sensitivity to quantify and to identify vanishingly small concentrations of key molecules. The ACQUITY UPLC M-Class System is ideally suited for a broad range of applications including proteomics, metabolic profiling, metabolite identification and pharmacokinetic studies. Its new 15k psi-capable ACQUITY UPLC M-Class Columns tap the potential of sub-2-micron particle technology, yielding faster separations, greater peak capacities and increased levels of sensitivity.

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The ACQUITY UPLC M-Class System was introduced at WCBP 2014 Symposium, a conference with a focus on analytical methods for biotechnology pharmaceuticals. Waters expects to commence shipments of the new system in the current fiscal quarter.

"When scientists doing proteomics or investigating new biopharmaceuticals talk to us about the work they do, they often speak of protein coverage or being able to quantify and identify incredibly small amounts of key molecules usually in the presence of much higher amounts of other molecules. This is difficult work without the appropriate tools. With the ACQUITY UPLC M-Class System, they will have the capability to peer into the unseen and achieve their research goals," said Art Caputo, President of the Waters Division. "As an LC inlet to mass spectrometers, the ACQUITY UPLC M-Class System empowers more scientists to reliably employ microscale chromatography in order to solve their most complex analytical challenges."

Nano- to microscale LC is defined by flow rates of 200 nL/min. to 100 microliter/min. with columns having an internal diameter of up to 1.0 mm. The advantages include the conservation of sample and solvent, increased sensitivity and a flow rate compatible with high sensitivity electrospray ionization (ESI) mass spectrometry (MS).

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