Dec. 9, 2013
/PRNewswire/ -- BioTrends Research Group, one of the world's leading research and advisory firms for specialized biopharmaceutical issues, finds that, one month post-launch in
the United States
, more than a quarter of surveyed U.S. medical oncologists have prescribed Boehringer Ingelheim's irreversible epidermal growth factor receptor (EGFR) inhibitor Gilotrif for the treatment of non-small-cell lung cancer (NSCLC). According to the first wave of the
report series, approximately three-quarters of current Gilotrif nonprescribers expect to prescribe Gilotrif to their treatment-naive,
mutation-positive metastatic NSCLC patients within the next six months.
The report also finds that over half of surveyed medical oncologists reported high favorability towards Gilotrif, and nearly two-thirds indicated a high interest level in learning more about the product. However, Gilotrif fails to significantly differentiate itself from Genentech/Roche/Chugai/Astellas' Tarceva for the treatment of
mutation-positive NSCLC patients in the first-line setting over most key metrics, including efficacy and tolerability attributes. Notably, the availability of Tarceva is one of the top reasons limiting use of Gilotrif in this indication, along with lack of familiarity with Gilotrif and cost.
"We also find that medical oncologists are moderately to highly interested in prescribing Gilotrif in new, additional patient populations and hope to see regulatory approval in these indications, including the
mutation-positive, EGFR TKI pretreated patient population and for patients harboring other
mutations, including those associated with resistance to Tarceva (e.g. T790M mutations)," said Decision Resources Group Business Insights Analyst Orestis Mavroudis-Chocholis, Ph.D. "Similarly, surveyed medical oncologists report that they are most likely to prescribe Gilotrif in these patient populations over other available therapies, including Tarceva and chemotherapy regimens."
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SOURCE BioTrends Research Group