"Our data provide the first true glimpse of the potential of this approach in patients with aggressive lymphomas that, until this point, were virtually untreatable," said study author James Kochenderfer, MD, of the Experimental Transplantation and Immunology Branch of the National Cancer Institute at the National Institutes of Health in Bethesda, Md. "We are particularly encouraged by the partial and complete responses that we observed in a number of patients with diffuse large B cell lymphomas who had exhausted all other treatment options. This approach offers an option for patients with chemotherapy-refractory large B cell lymphomas who are not generally thought to be good candidates for hematopoietic stem cell transplantation. This approach is still an early-stage experimental therapy, and we will continue our research to further improve the protocol and evaluate its value in additional patients with treatment-resistant disease."Dr. Kochenderfer will present this study during an oral presentation at 6:15 p.m. CST on Sunday, December 8, in Riverside Rooms R02-R03 of the Ernest N. Morial Convention Center.
High-Tech Advances In Gene Therapy Overcome Challenges, Offer Hope For Patients With Hard-to-Treat Blood Disorders
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