This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here
Stocks Under $10 with 50-100% upside potential - 14 days FREE!

Gilead To Present Data On Oncology Pipeline At American Society Of Hematology Annual Meeting

Gilead Sciences, Inc. (NASDAQ: GILD) today announced that 10 abstracts describing the company's investigational agents for several hematological malignancies have been selected for presentation at the Annual Meeting of the American Society of Hematology (ASH) taking place December 7-10 in New Orleans. The abstracts describe clinical and pre-clinical data from studies of idelalisib, which is currently under review by the U.S. Food and Drug Administration for treatment of refractory indolent non-Hodgkin’s lymphoma (iNHL), as well as for GS-9973, GS-9820 and momelotinib (formerly CYT387 / GS-0387). Detailed results from these studies will be presented at the conference.

“We are encouraged by the data across our hematologic oncology pipeline that will be presented at the ASH annual meeting,” said Roy Baynes, MD, PhD, Senior Vice President of Oncology and Inflammation Therapeutics at Gilead Sciences. “We are moving forward quickly to fully explore the potential clinical benefit of idelalisib and other investigational agents against a range of hematological cancers.”

Presentations on idelalisib, Gilead's investigational, targeted, oral inhibitor of PI3K delta include:

  • Updated data from a Phase 2 study (Study 101-09) in patients with highly refractory iNHL (#85). The results of this trial support Gilead’s regulatory filings for idelalisib for the treatment of iNHL.
  • Analyses from a Phase 1b study (Study 101-07) of idelalisib in combination with currently approved therapies for the treatment of relapsed/refractory chronic lymphocytic leukemia (CLL) (#4180, #4176 and #2878).
  • An analysis from Phase 1b and 2 studies (Studies 101-07 and 101-08) comparing responses among CLL patients with high risk prognostic markers (Del(17p)/TP53 mutation, Del(11q), IgHV mutation and NOTCH1 mutation) to CLL patients without these markers (#1632).
  • The first pre-clinical data demonstrating the potential of idelalisib for the treatment of myelofibrosis (#4065).

Clinical data on other oral investigational compounds in development for the treatment of hematologic malignancies also will be presented, including:

  • Momelotinib, a selective inhibitor of JAK1 and JAK2: Updated safety and efficacy results from a Phase 1/2 study in myelofibrosis (#108). The Phase 3 clinical program for momelotinib will be initiated this quarter.
  • GS-9973, a selective inhibitor of spleen tyrosine kinase (Syk): Initial results from a Phase 2 study in CLL and non-Hodgkin lymphoma (NHL) (#1634). GS-9973 is being evaluated in Phase 2 studies as both a single agent (Study 102) and in combination with idelalisib (Study 103) in patients with relapsed or refractory CLL, iNHL and other lymphoid malignancies.
  • GS-9820, a second-generation inhibitor of PI3K delta: Data from a Phase 1b dose escalation monotherapy study for recurrent CLL or iNHL (#2881).

Abstracts for Gilead's presentations can be accessed at http://www.hematology.org/Meetings/Annual-Meeting/. Further information about the clinical studies described above can be found at  www.clinicaltrials.gov.

Idelalisib, momelotinib, GS-9973 and GS-9820, each as single-agents and in combination with other agents, are investigational products, and their safety and efficacy have not been established.

1 of 3

Select the service that is right for you!

COMPARE ALL SERVICES
Action Alerts PLUS
Try it NOW

Jim Cramer and Stephanie Link actively manage a real portfolio and reveal their money management tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
  • Weekly roundups
TheStreet Quant Ratings
Try it NOW
Only $49.95/yr

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
  • Upgrade/downgrade alerts
Stocks Under $10
Try it NOW

David Peltier, uncovers low dollar stocks with extraordinary upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
  • Weekly roundups
Dividend Stock Advisor
Try it NOW

Jim Cramer's protege, David Peltier, identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Alerts when market news affect the portfolio
  • Bi-weekly updates with exact steps to take - BUY, HOLD, SELL
Real Money Pro
Try it NOW

All of Real Money, plus 15 more of Wall Street's sharpest minds delivering actionable trading ideas, a comprehensive look at the market, and fundamental and technical analysis.

Product Features:
  • Real Money + Doug Kass Plus 15 more Wall Street Pros
  • Intraday commentary & news
  • Ultra-actionable trading ideas
Options Profits
Try it NOW

Our options trading pros provide daily market commentary and over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.

Product Features:
  • 100+ monthly options trading ideas
  • Actionable options commentary & news
  • Real-time trading community
  • Options TV
To begin commenting right away, you can log in below using your Disqus, Facebook, Twitter, OpenID or Yahoo login credentials. Alternatively, you can post a comment as a "guest" just by entering an email address. Your use of the commenting tool is subject to multiple terms of service/use and privacy policies - see here for more details.
Submit an article to us!
DOW 16,985.61 +78.99 0.47%
S&P 500 1,972.83 +9.12 0.46%
NASDAQ 4,419.0340 +27.5710 0.63%

Brokerage Partners

Rates from Bankrate.com

  • Mortgage
  • Credit Cards
  • Auto
Advertising Partners

Free Newsletters from TheStreet

My Subscriptions:

After the Bell

Before the Bell

Booyah! Newsletter

Midday Bell

TheStreet Top 10 Stories

Winners & Losers

Register for Newsletters
Top Rated Stocks Top Rated Funds Top Rated ETFs