This Day On The Street
Continue to site
This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here

NIH-sponsored Consortium Of Food Allergy Research (CoFAR) Starts A Phase II Clinical Study With DBV Technologies' Viaskin(R) Peanut In The Treatment Of Peanut Allergy

  • Leading US centers in food allergy will be involved in an NIH-funded CoFAR study, coordinated by Dr. Sampson and Dr. Jones in collaboration with DBV' team
  • CoFAR6 study will help to better characterize the mechanisms of action of epicutaneous immunotherapy

NEW YORK, and BAGNEUX, France, Oct. 24, 2013 (GLOBE NEWSWIRE) -- DBV Technologies (Euronext: DBV - ISIN: FR0010417345), creator of Viaskin®, a new approach in the treatment of allergies, and the Consortium For Food Allergy Research (CoFAR) announced today that the CoFAR started enrolling patients into a multi-center, randomized, double-blinded, placebo-controlled trial using Viaskin® Peanut to treat children and adults with peanut allergy. The trial "Epicutaneous Immunotherapy (EPIT) for Peanut Allergy: A Randomized, Double-Blind, Placebo-Controlled, Phase II study in Children and Adult" is also known as CoFAR6.

The CoFAR6 study, coordinated by Dr. Hugh Sampson of The Icahn School of Medicine at Mount Sinai (NY) and Dr. Stacie Jones of Arkansas Children's Hospital, will enroll 75 patients from 4 to 25 years of age in the US. Patients will be randomized to two doses of Viaskin® Peanut (100µg or 250µg) versus placebo (1:1:1). Viaskin® Peanut will be applied once a day. Clinical efficacy will be evaluated after 12 months and 30 months of treatment. Immunological status will be assessed at baseline, 1 year and 2.5 years. Safety will be monitored centrally. 

Dr. Hugh Sampson, Kurt Hisrchhorn Professor of Pediatrics, Director of the Jaffe Food Allergy Institute and Dean of Translational Biomedical Science at The Mount Sinai Medical Center in New York (USA) is the principal investigator of the CoFAR6 study. He said: "We are delighted to initiate this clinical trial with Viaskin® Peanut in an effort to characterize how food proteins processed through the cutaneous immune system may alter the allergic response." Dr. Sampson is also international coordinator for 'VIPES' (Viaskin Peanut Efficacy and Safety study), DBV's global Phase IIb clinical trial to evaluate Viaskin® Peanut efficacy and safety.  

Dr. Stacie Jones, Professor of Pediatrics at the University of Arkansas for Medical Sciences, Chief of Allergy and Immunology and King Chair in Pediatric Allergy at Arkansas Children's Hospital in Little Rock (USA) said: "We are excited about the next phase of study for this new therapy that, if effective, will give peanut allergic patients a much needed treatment option for the future." Previously, Dr. Jones participated actively as one of the Principal Investigators in DBV's Phase Ib study on Viaskin® Peanut.

"We are proud to work with the Consortium of Food Allergy Research, a leading clinical research network in search of effective treatments for food allergies." said Dr. Pierre-Henri Benhamou, Chairman and CEO of DBV Technologies . "The goal of Viaskin® is to safely treat life-threatening allergies, such as peanut allergy, by triggering a specific, robust immune response in the skin. CoFAR6 will help characterize more accurately the immunological mechanism of action of Epicutaneous Immunotherapy. DBV shares a strong commitment with CoFAR to find a therapeutic solution for food allergy, which has become a serious public health concern."

About CoFAR

The Consortium of Food Allergy Research (CoFAR) was established in July 2005 by the National Institute of Allergy and Infectious Diseases, a part of the National Institutes of Health, to conduct both observational and clinical studies to answer questions related to food allergies. Study sites include: The Mount Sinai Medical Center (New York); Johns Hopkins University (Baltimore); National Jewish Health (Denver); University of Arkansas for Medical Sciences (Little Rock); and, University of North Carolina (Chapel Hill).  

About peanut allergy : a life-threatening risk for millions of people

Peanut allergy affects both adults and children. In the US, about 1.1% of the general population, or over 3 million people, are allergic to peanuts and in the United Kingdom, it has been estimated that peanut allergy affects 1.8% of young children. The prevalence of peanut allergy in other Western countries (e.g., Canada, France and Spain) has been studied by many researchers, and the prevalence ranges from 0.9% to 1.5%. Peanut allergy is persistent throughout life; many studies indicate that fewer than 20% of young children allergic to peanut will outgrow their allergy. The allergic reaction to peanut can range from mild to severe, and in rare cases can be life threatening.

1 of 3

Check Out Our Best Services for Investors

Action Alerts PLUS

Portfolio Manager Jim Cramer and Director of Research Jack Mohr reveal their investment tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
Quant Ratings

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
Stocks Under $10

David Peltier uncovers low dollar stocks with serious upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
14-Days Free
Only $9.95
14-Days Free
Dividend Stock Advisor

David Peltier identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Updates with exact steps to take - BUY, HOLD, SELL
Trifecta Stocks

Every recommendation goes through 3 layers of intense scrutiny—quantitative, fundamental and technical analysis—to maximize profit potential and minimize risk.

Product Features:
  • Model Portfolio
  • Intra Day Trade alerts
  • Access to Quant Ratings
Real Money

More than 30 investing pros with skin in the game give you actionable insight and investment ideas.

Product Features:
  • Access to Jim Cramer's daily blog
  • Intraday commentary and news
  • Real-time trading forums
Only $49.95
14-Days Free
14-Days Free
YHOO $37.03 2.90%
AAPL $93.12 -0.53%
FB $117.91 -0.13%
GOOG $701.92 0.89%
TSLA $213.94 -3.90%


Chart of I:DJI
DOW 17,650.65 -0.61 -0.00%
S&P 500 2,049.81 -1.31 -0.06%
NASDAQ 4,720.7820 -4.8570 -0.10%

Free Reports

Top Rated Stocks Top Rated Funds Top Rated ETFs